Einstein Posted January 18 Share Posted January 18 Chinese scientists ‘create’ mutant Coronavirus with 100% kill rate in Mice: Alina Chan reacts https://thehill.com/video/chinese-scientists-‘create’-mutant-coronavirus-with-100-kill-rate-in-mice-alina-chan-reacts/9337257/ Quote Link to comment Share on other sites More sharing options...
ChevyVanMiller Posted January 18 Share Posted January 18 China is truly going to be the death of us all. 2 Quote Link to comment Share on other sites More sharing options...
That's No Moon Posted January 18 Share Posted January 18 Well great. Good job. So when it gets out in China next time everyone listen to the lockdown so they only eliminate themselves 1 Quote Link to comment Share on other sites More sharing options...
Wacka Posted January 18 Share Posted January 18 The Hil-l a well known scientific journal. Quote Link to comment Share on other sites More sharing options...
Warcodered Posted January 18 Share Posted January 18 As terrifying as a 100% kill rate sounds unless it incubates for a long ass time or something it kind of kills itself. Quote Link to comment Share on other sites More sharing options...
Einstein Posted January 18 Author Share Posted January 18 25 minutes ago, Wacka said: The Hil-l a well known scientific journal. https://www.biorxiv.org/content/10.1101/2024.01.03.574008v1.full 1 Quote Link to comment Share on other sites More sharing options...
Doc Posted January 18 Share Posted January 18 But there was no gain of function research being done, and it didn’t leak from the lab… 2 4 Quote Link to comment Share on other sites More sharing options...
EasternOHBillsFan Posted January 19 Share Posted January 19 I wish more people were worried about climate change which affects us all instead of this China scare nonsense... 3 1 3 Quote Link to comment Share on other sites More sharing options...
PetermansRedemption Posted January 19 Share Posted January 19 At least the Chinese have an impeccable safety record and no history of lab leaks 😗 1 Quote Link to comment Share on other sites More sharing options...
Buffalo716 Posted January 19 Share Posted January 19 ***** we're doomed 6 months till it escapes this laboratory 2 Quote Link to comment Share on other sites More sharing options...
Bill from NYC Posted January 19 Share Posted January 19 5 hours ago, Buffalo716 said: ***** we're doomed 6 months till it escapes this laboratory Of course. Quote Link to comment Share on other sites More sharing options...
Ridgewaycynic2013 Posted January 19 Share Posted January 19 (edited) 6 hours ago, Buffalo716 said: ***** we're doomed 6 months till it escapes this laboratory 1 hour ago, Bill from NYC said: Of course. Never happen. There will be no customers for all that crap from temu.com. 🤔🤨 Edited January 19 by Ridgewaycynic2013 1 1 Quote Link to comment Share on other sites More sharing options...
Another Fan Posted January 19 Share Posted January 19 6 hours ago, Buffalo716 said: ***** we're doomed 6 months till it escapes this laboratory This will be the year then the Bills win the Super Bowl 😄 1 Quote Link to comment Share on other sites More sharing options...
Punching Bag Posted January 19 Share Posted January 19 20 hours ago, Einstein said: Chinese scientists ‘create’ mutant Coronavirus with 100% kill rate in Mice: Alina Chan reacts https://thehill.com/video/chinese-scientists-‘create’-mutant-coronavirus-with-100-kill-rate-in-mice-alina-chan-reacts/9337257/ China does have a population problem. Maybe this is their solution. Quote Link to comment Share on other sites More sharing options...
Jauronimo Posted January 19 Share Posted January 19 https://www.wsj.com/world/china/chinese-lab-mapped-deadly-coronavirus-two-weeks-before-beijing-told-the-world-documents-show-9bca8865 Wow. In addition to being highly lethal, this new strain makes bats even more delicious. I didn't think that was even possible. 1 Quote Link to comment Share on other sites More sharing options...
Jon in Pasadena Posted January 19 Share Posted January 19 Next time I'm a mouse, I'll be very concerned. Quote Link to comment Share on other sites More sharing options...
BringBackFergy Posted January 19 Share Posted January 19 @Beck Water Keep us up to date. You know this stuff. Quote Link to comment Share on other sites More sharing options...
Beck Water Posted January 19 Share Posted January 19 (edited) On 1/18/2024 at 1:37 PM, Einstein said: Chinese scientists ‘create’ mutant Coronavirus with 100% kill rate in Mice: Alina Chan reacts https://thehill.com/video/chinese-scientists-‘create’-mutant-coronavirus-with-100-kill-rate-in-mice-alina-chan-reacts/9337257/ It's always nice to do a little digging before one propegates fear mongering headlines, and while putting "create" mutant coronavirus isn't as bad as some, there are a lot of them out there. 1 hour ago, BringBackFergy said: @Beck Water Keep us up to date. You know this stuff. Yeah, I've been following this. Here's the paper if anyone cares https://www.biorxiv.org/content/10.1101/2024.01.03.574008v1.full Note that biorx server is NOT a peer reviewed journal. They didn't invite other scientists to look at their study design or results and critique. That matters. Bottom line up front: it appears real. there are legitimate and real concerns about this kind of work, but the result of this is likely not as alarming as headlines are making it sound. Snopes does a pretty good job dissecting it. https://www.snopes.com/news/2024/01/18/chinese-mutant-covid-19/ First, it's not Sars-CoV2 the virus that causes Covid, it's a pangolin coronavirus GX_P2V that's like a "cousin" of Sars-CoV2, isolated in 2017. Second, the virus mutated while being propagated in cell culture, this wasn't genetic engineering to cause gain of function. As Snopes notes: "The virus mutated from its original isolate, but it is a bit unfair to claim that the scientists "created" the virus. Since coronaviruses (and viruses in general) are known to rapidly mutate their genetic instructions, it is unsurprising that the virus used in the study mutated from the time it was isolated. In the paper (and in prior research by the same group), the researchers note that this particular variant of GX_P2V contained the mutation because it had better adapted to the cell cultures in which it was grown." In simple terms, mutating is what RNA viruses do...they're slobs (technical talk: RNA viruses have a naturally lower fidelity of replication, so they incorporate 'mistakes' more often. Mistakes that provide a competitive advantage to the virus = mutation) Third, the genetic engineering took place in the mice, who were given gene to express the human receptor proteins Covid binds to and uses to enter cells (technically: hACE2). But of course, that's all the humanity they gave the mice; we don't know how that genetic change affects the murine immune system or how high lethality in hACE2 mice would translate to a human population, or even.....a larger number of mice because.........wait for it..... Fourth: we're talking FOUR mice. They injected FOUR mice, and they all died. "All died" is bad, but four is a damned small sample size. I want to know what the mortality rate in these mice is, in their transgenic mouse facility, under normal conditions. Lots of other questions. Last but not least, there's a fair amount of moral indignation in the scientific community over this whole line of research and its risks vs. potential learnings and possible benefits in the first place. Rightfully so IMHO: Quote The main concern from scientists revolved around whether the study was worth conducting in the first place, given the inherent risk of the research. Ensuring that research is conducted safely and responsibly has been a major talking point in the field since the start of the COVID-19 pandemic. If it would persuade China to for-real start treating wet markets like a problem and to crack down on the black-market trade in pangolins and pangolin parts, it might do some good. That's all I got for ya right now @BringBackFergy, hope it helps. If anything unclear, ask. Edited January 19 by Beck Water 4 2 1 Quote Link to comment Share on other sites More sharing options...
BringBackFergy Posted January 19 Share Posted January 19 18 minutes ago, Beck Water said: It's always nice to do a little digging before one propegates fear mongering headlines, and while putting "create" mutant coronavirus isn't as bad as some, there are a lot of them out there. Yeah, I've been following this. Here's the paper if anyone cares https://www.biorxiv.org/content/10.1101/2024.01.03.574008v1.full Note that biorx server is NOT a peer reviewed journal. They didn't invite other scientists to look at their study design or results and critique. That matters. Bottom line up front: it appears real. there are legitimate and real concerns about this kind of work, but the result of this is likely not as alarming as headlines are making it sound. Snopes does a pretty good job dissecting it. https://www.snopes.com/news/2024/01/18/chinese-mutant-covid-19/ First, it's not Sars-CoV2 the virus that causes Covid, it's a pangolin coronavirus GX_P2V that's like a "cousin" of Sars-CoV2, isolated in 2017. Second, the virus mutated while being propagated in cell culture, this wasn't genetic engineering to cause gain of function. As Snopes notes: "The virus mutated from its original isolate, but it is a bit unfair to claim that the scientists "created" the virus. Since coronaviruses (and viruses in general) are known to rapidly mutate their genetic instructions, it is unsurprising that the virus used in the study mutated from the time it was isolated. In the paper (and in prior research by the same group), the researchers note that this particular variant of GX_P2V contained the mutation because it had better adapted to the cell cultures in which it was grown." In simple terms, mutating is what RNA viruses do...they're slobs (technical talk: RNA viruses have a naturally lower fidelity of replication, so they incorporate 'mistakes' more often. Mistakes that provide a competitive advantage to the virus = mutation) Third, the genetic engineering took place in the mice, who were given gene to express the human receptor proteins Covid binds to and uses to enter cells (technically: hACE2). But of course, that's all the humanity they gave the mice; we don't know how that genetic change affects the murine immune system or how high lethality in hACE2 mice would translate to a human population, or even.....a larger number of mice because.........wait for it..... Fourth: we're talking FOUR mice. They injected FOUR mice, and they all died. "All died" is bad, but four is a damned small sample size. I want to know what the mortality rate in these mice is, in their transgenic mouse facility, under normal conditions. Lots of other questions. Last but not least, there's a fair amount of moral indignation in the scientific community over this whole line of research and its risks vs. potential learnings and possible benefits in the first place. Rightfully so IMHO: If it would persuade China to for-real start treating wet markets like a problem and to crack down on the black-market trade in pangolins and pangolin parts, it might do some good. That's all I got for ya right now @BringBackFergy, hope it helps. If anything unclear, ask. So, should the CDC start their own “response” research to look for a vax in the event this thing is unleashed? How do they do that if the virus is unique to China labs (i.e. we don’t have access to this new “super virus”)? Quote Link to comment Share on other sites More sharing options...
Beck Water Posted January 20 Share Posted January 20 (edited) 12 minutes ago, BringBackFergy said: So, should the CDC start their own “response” research to look for a vax in the event this thing is unleashed? How do they do that if the virus is unique to China labs (i.e. we don’t have access to this new “super virus”)? My take for whatever it's worth, is "Nah". For one thing, it's not clear that it's a "super virus" to anything in the wild. There are a number of things that, if you're forcibly infected with a significant amount, might kill you but that aren't particularly good at spreading on their own. For research on a potential vaccine, we have the published genetic sequence of this ***** (Genbank Accession #MT072864) and the beauty of mRNA vaccines is, that could be all we need. It's worth having a look at that, and someone probably is. Edited January 20 by Beck Water 1 Quote Link to comment Share on other sites More sharing options...
Captain_Quint Posted January 20 Share Posted January 20 On 1/18/2024 at 2:43 PM, ChevyVanMiller said: China is truly going to be the death of us all. Maybe not all of us: 1 Quote Link to comment Share on other sites More sharing options...
boyst Posted January 20 Share Posted January 20 :yawn: Quote Link to comment Share on other sites More sharing options...
Nextmanup Posted January 21 Share Posted January 21 On 1/18/2024 at 9:40 PM, EasternOHBillsFan said: I wish more people were worried about climate change which affects us all instead of this China scare nonsense... Yeah but we ain't gonna do squat about climate change. I personally do believe the Earth is one of its MANY periodic climate change transitions right now...but what the heck are we gonna do about it? I am looking forward to Miami Beach being under water however; I live about an hour north of Miami and SE FL is real shithole. Quote Link to comment Share on other sites More sharing options...
Augie Posted January 21 Share Posted January 21 This kinda puts a little more pressure on the “Win One Before I Die” crowd. 2 Quote Link to comment Share on other sites More sharing options...
AlCowlingsTaxiService Posted January 21 Share Posted January 21 On 1/18/2024 at 2:37 PM, Einstein said: Chinese scientists ‘create’ mutant Coronavirus with 100% kill rate in Mice: Alina Chan reacts https://thehill.com/video/chinese-scientists-‘create’-mutant-coronavirus-with-100-kill-rate-in-mice-alina-chan-reacts/9337257/ Well, cmon now … it’s The Hill! Right up there with the New England Journal of Medicine. Beware! Quote Link to comment Share on other sites More sharing options...
WhoTom Posted January 21 Share Posted January 21 1 hour ago, Augie said: This kinda puts a little more pressure on the “Win One Before I Die” crowd. Yeah, more like "Win one before humanity makes itself extinct." Quote Link to comment Share on other sites More sharing options...
stuvian Posted January 21 Share Posted January 21 it's Chinese so I'm sure we'll come back to life 30 minutes later On 1/19/2024 at 4:34 PM, Jon in Pasadena said: Next time I'm a mouse, I'll be very concerned. the copyright on Mickey Mouse has just expired. Coincidence? I think not Quote Link to comment Share on other sites More sharing options...
Warcodered Posted January 21 Share Posted January 21 5 hours ago, Augie said: This kinda puts a little more pressure on the “Win One Before I Die” crowd. Humanity goes extinct.....but the important thing is the Bills managed to win the Super Bowl before it all came to an end. You have to have your priorities. 2 Quote Link to comment Share on other sites More sharing options...
Bookie Man Posted January 22 Share Posted January 22 Damn, I come to OTW to get my mind of losing to the Chefs and I get this thread?!?! Lol Quote Link to comment Share on other sites More sharing options...
BillsShredder83 Posted January 24 Share Posted January 24 On 1/18/2024 at 2:53 PM, That's No Moon said: Well great. Good job. So when it gets out in China next time everyone listen to the lockdown so they only eliminate themselves whole thing sounds like psyop to produce your exact reaction. it might get me to wash my hands after "only" peeing though Quote Link to comment Share on other sites More sharing options...
Simon Posted January 25 Share Posted January 25 8 hours ago, BillsShredder83 said: whole thing sounds like psyop to produce your exact reaction. it might get me to wash my hands after "only" peeing though Squid: In the Navy, they taught us to wash our hands after we pee. Jar Head: In the Marines, they taught us not to piss on our hands. 3 Quote Link to comment Share on other sites More sharing options...
That's No Moon Posted January 25 Share Posted January 25 On 1/24/2024 at 1:47 PM, BillsShredder83 said: whole thing sounds like psyop to produce your exact reaction. it might get me to wash my hands after "only" peeing though Yeah that must be it. Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You can post now and register later. If you have an account, sign in now to post with your account.