Know anyone with a disease? Read this

[Wacka]

Bob, Please put down the bong!

[Deranged Rhino]

Just now, Wacka said:

Bob, Please put down the bong!

 

Bob's live webcam: 

[KRC]

1 hour ago, Bob in Mich said:

 

Are you trolling or just stupid, Jim?   I ask because it has to be one or the other? 

 

You need to learn to relax, Bob. Way to stressed out about a message board. Every hear of marijuana? I hear it can help you relax.

[Bob in Mich]

31 minutes ago, KRC said:

 

You need to learn to relax, Bob. Way to stressed out about a message board. Every hear of marijuana? I hear it can help you relax.

 

See KFC here gets it.  Thanks pal, a fine idea.......better now.

 

[B-Man]

 

 

Which Country Smokes the Most Weed? It’s Probably Not Who You Think.

I’m referring to national cannabis consumption rates, AKA the percentage of residents in any one country who consume cannabis.

 

With our rapidly expanding regulated cannabis programs and national high anxiety, it must be the US, right? Everyone I know is high, so USA #1!

 

Nope.

 

Nor is it Canada, even with their recent national legalization of cannabis, and easy access to Tim Hortons.

 

The place with the highest rate of cannabis consumption isn’t who you would think, nor is it someplace many ‘muricans could find on a map

 

— Nigeria.

 

 

I would have guessed Jamaica long before getting to Nigeria.

 

 

Nigeria -- the healthiest country on earth.....................

 

 

.

 

[KRC]

8 minutes ago, Bob in Mich said:

 

See KFC here gets it.  Thanks pal, a fine idea.......better now.

 

 

I've got the munchies. Now, do I go with fried chicken or Doritos?

[B-Man]

2 minutes ago, KRC said:

 

I've got the munchies. Now, do I go with fried chicken or Doritos?

 

 

 

No need to worry.

 

 

 

[row_33]

I learned today that my internal organs communicate with each other through like cells you know

 

 

 

[DC Tom]

3 minutes ago, row_33 said:

I learned today that my internal organs communicate with each other through like cells you know

 

 

 

 

Give him a break.  It was a proper use of the term - communication pathways between biological cells in the body.

 

It was so broad as to be completely meaningless, and represents a gross misunderstanding of the biological role of the endocannabinoid system.  But it at least was the proper term for what he's so ignorant about.

[Koko78]

13 minutes ago, DC Tom said:

 

Give him a break.  It was a proper use of the term - communication pathways between biological cells in the body.

 

It was so broad as to be completely meaningless, and represents a gross misunderstanding of the biological role of the endocannabinoid system.  But it at least was the proper term for what he's so ignorant about.

 

Does that make him a proper idiot?

[3rdnlng]

Maybe we could come up with a little ditty like this for our organs to help with our communications.

 

 

[Chef Jim]

4 hours ago, DC Tom said:

 

  Self-important, much.

 

Bob at the tailgate. 

 

 

3 hours ago, Deranged Rhino said:

 

Bob's live webcam: 

 

Jesus.  I get major anxiety just looking at that.  

[Deranged Rhino]

2 minutes ago, Chef Jim said:

Jesus.  I get major anxiety just looking at that.  

 

+1. That would destroy me, and I'd be coughing for months.

[Albwan]

   Pot was fun back in the day when it was illegal, now that everyone is doing it, it's just

not cool anymore. I mean  it seems every walmart employee smokes. yikes.

No wonder Peter strozk was calling them the smelly walmart people.

[Chef Jim]

5 minutes ago, Deranged Rhino said:

 

+1. That would destroy me, and I'd be coughing for months.

 

I have zero desire to do a bong hit nowadays.  Funny because the bong was my favorite way to smoke years and years ago.  Not 4g's would likely last me 6 months.  

[row_33]

The UK has gone the opposite way on legislation, after fully realizing the serious damage this stuff causes to people, especially those who cannot afford the effects of it

 

 

[Chef Jim]

3 hours ago, B-Man said:

 

 

 

No need to worry.

 

 

 

 

As a Chef I disapprove of this message.  

[Bob in Mich]

On 6/4/2019 at 11:51 AM, Chef Jim said:

 

You really think doctors don’t know that there is communication between all the cells and organs of the human body?  Yeah you’re high. 

 

 

You sort of misstated what I said to give yourself a shot at a cute reply or so it seems. 

 

All doctors know cells communicate.  Only those that understand the workings of the endocannabinoid system however know that this signaling should be taking place and so know better how to treat their patients when it is not.  

 

What I said was:

 

"You may be comfortable with a doctor that doesn't know about a cellular communication network present in nearly every organ, but I am not.  I would prefer a doctor that actually knew how and why he was treating me rather than one that didn't and worse yet, didn't feel the need to learn. "

 

 

Obviously some here know all of there is to know about the endocannabinoid system but for those that may still have questions this Q&A article explains its importance.

 

http://www.projectcbd.org/science/endocannabinoid-system-and-biology-wellness

 

from the article

Project CBD: Greg, as a neuroscientist I think you could shed light on some basic questions I think a lot of people have as interest in cannabis therapeutics has grown so dramatically around the country. Let’s start with the endocannabinoid system, why cannabis works. What is the endocannabinoid system? Why is it important?

 

Gerdeman: The endocannabinoid system is really how cannabis works in the body. Although cannabis has many different chemical constituents and it interacts in the body in a lot of dynamic ways. But really, I think one of the biggest breakthroughs in biomedical science is in the last hundred years, is understanding the receptors that THC and other cannabinoids interact with. And, the body’s own THC-like molecules, and the family of molecules that we call the endocannabinoids and how they interact with cells, with organs, with entire systems of the human being and other animals. And now we have gotten a really strong understanding of how much the physiology of humans is integrated using the endocannabinoid system. It helps organ systems and signaling systems like your hormones and your nervous system and your immune system, your gut, it helps that interaction actually get accomplished – these signaling molecules that act very much like THC

 

 

[unbillievable]

After 73 pages, I now understand that Popeye wasn't really eating spinach...

[McGee Return TD]

On 7/20/2014 at 10:55 PM, 3rdnlng said:

Love your passion and will evaluate your links (somewhat). 

 

My how things change!

[3rdnlng]

11 minutes ago, unbillievable said:

After 73 pages, I now understand that Popeye wasn't really eating spinach...

Steroids for sure, but some real ***** up stuff. Huge forearms, no biceps and a chest like the proverbial 97 pound weakling.

[Bob in Mich]

4 minutes ago, 3rdnlng said:

Steroids for sure, but some real ***** up stuff. Huge forearms, no biceps and a chest like the proverbial 97 pound weakling.

 

Maybe, but he was strong to the finish

[Bob in Mich]

On 6/4/2019 at 11:08 AM, DC Tom said:

 

You claim pot cures "disease," and your primary source for medical information is leafy.com.  Just ***** off.

 

Tommy, you dog!  Here for what now, almost 5 years, you have lead us all to believe that you were an ignorant #######.  You dog!  You were playing possum weren't you?  You knew all this stuff all along but just pretended to be a stupid fukstick.  Gosh, I am embarrassed as I was fooled into thinking you were really just a huge *****.

 

Anyway, I found a daily leafy.com article for you....especially for you, knowing what we now know, eh?

 

https://www.leafly.com/news/industry/turn-a-college-degree-into-a-cannabis-career

[Chef Jim]

Are you high Bob?  Because you sound high again.  You said I misstated what you said. You said (and you quoted it again):

 

You may be comfortable with a doctor that doesn't know about a cellular communication network present in nearly every organ, but I am not.

 

And followed it up with this:

 

All doctors know cells communicate.

 

Which is it Bob? Do they or do they not know that cells communicate? 

[Bob in Mich]

59 minutes ago, Chef Jim said:

Are you high Bob?  Because you sound high again.  You said I misstated what you said. You said (and you quoted it again):

 

You may be comfortable with a doctor that doesn't know about a cellular communication network present in nearly every organ, but I am not.

 

And followed it up with this:

 

All doctors know cells communicate.

 

Which is it Bob? Do they or do they not know that cells communicate? 

 

Intentionally confused?  Seems so but ok.  Just because a doctor can infer that cells are communicating does not mean he/she understands the endocannabinoid system or how to treat an apparent problem with that communication network. 

 

Epidiolex, the cannabis based epilepsy drug, seems to reduce seizures dramatically.  It operates on the endocannabinoid system and seems to dampen over activity.  It was recently approved by the FDA to treat epileptic children.

 

Would you want to take your (hypothetically) epileptic child to a doctor that understands the faulty signaling mechanism or an under educated doctor that does not?  While both doctors may know that something is wrong with your kid, one will know how to address the problem and one likely will not. 

Edited June 6, 2019 by Bob in Mich

[row_33]

two friends said they knew someone for whom pot cured their bubonic plaugue

 

too bad doctors aren't up on all these research methods

 

 

[McGee Return TD]

Just now, row_33 said:

two friends said they knew someone for whom pot cured their bubonic plaugue

 

too bad doctors aren't up on all these research methods

 

 

 

Can't spell, terrible insult

 

 

 

[Bob in Mich]

2 minutes ago, row_33 said:

two friends said they knew someone for whom pot cured their bubonic plaugue

 

too bad doctors aren't up on all these research methods

 

 

 

Why not skip your monthly flea and tick meds and go visit those friends?  See if you can sleep in the room they keep their pet rat

[row_33]

13 minutes ago, McGee Return TD said:

 

Can't spell, terrible insult

 

 

 

 

maybe smoke up and all my troubles go away

 

for a few minutes

 

alright McGee, you'll get your next spelling error with 100 of these attached to it, should be happening very very shortly.... 

 

 

[Chef Jim]

1 hour ago, Bob in Mich said:

 

Intentionally confused?  Seems so but ok.  Just because a doctor can infer that cells are communicating does not mean he/she understands the endocannabinoid system or how to treat an apparent problem with that communication network. 

 

Epidiolex, the cannabis based epilepsy drug, seems to reduce seizures dramatically.  It operates on the endocannabinoid system and seems to dampen over activity.  It was recently approved by the FDA to treat epileptic children.

 

Would you want to take your (hypothetically) epileptic child to a doctor that understands the faulty signaling mechanism or an under educated doctor that does not?  While both doctors may know that something is wrong with your kid, one will know how to address the problem and one likely will not. 

 

So are you saying Dr 420 is the only doctor that would understand these things?  How you any of us know the level of knowledge the doctor we see has.   Regarding the part in bold which two doctors are we talking about and where does your miracle drug come into play here. 

[McGee Return TD]

3 minutes ago, Chef Jim said:

 

So are you saying Dr 420 is the only doctor that would understand these things?  How you any of us know the level of knowledge the doctor we see has.   Regarding the part in bold which two doctors are we talking about and where does your miracle drug come into play here. 

 

How you any of us know the level of knowledge the doctor we see has.

 

[Chef Jim]

15 minutes ago, McGee Return TD said:

 

How you any of us know the level of knowledge the doctor we see has.

 

 

I take it you're stoned too?  

[DC Tom]

1 hour ago, row_33 said:

two friends said they knew someone for whom pot cured their bubonic plaugue

 

too bad doctors aren't up on all these research methods

 

 

 

You have a 2 in 3 chance of surviving plague, without treatment.

 

That's not "cured."

[Bob in Mich]

18 minutes ago, Chef Jim said:

 

So are you saying Dr 420 is the only doctor that would understand these things?  How you any of us know the level of knowledge the doctor we see has.   Regarding the part in bold which two doctors are we talking about and where does your miracle drug come into play here. 

 

Why the intentional confusion today?  A doctor knowledgeable in the body's endocannabinoid system is the doctor more likely to know that a cannabinoid related signaling flaw is causing the problem with the epileptic child.  Rather than running through the traditional course of maybe a dozen epilepsy medicines, the educated doctor is able to home in on the cannabis based solution much sooner, perhaps saving the child's life.

[unbillievable]

7 minutes ago, Bob in Mich said:

 

Why the intentional confusion today?  A doctor knowledgeable in the body's endocannabinoid system is the doctor more likely to know that a cannabinoid related signaling flaw is causing the problem with the epileptic child.  Rather than running through the traditional course of maybe a dozen epilepsy medicines, the educated doctor is able to home in on the cannabis based solution much sooner, perhaps saving the child's life.

There's an easier solution.

 

A Coworker kept changing doctors until he found one that prescribed weed for his back pain.

 

[Chef Jim]

7 minutes ago, unbillievable said:

There's an easier solution.

 

A Coworker kept changing doctors until he found one that prescribed weed for his back pain.

 

 

That's what I did.  Then the weed did absolutely nothing.  I met with a neurosurgeon who fixed the problem. Pain free since. 

18 minutes ago, Bob in Mich said:

 

Why the intentional confusion today?  A doctor knowledgeable in the body's endocannabinoid system is the doctor more likely to know that a cannabinoid related signaling flaw is causing the problem with the epileptic child.  Rather than running through the traditional course of maybe a dozen epilepsy medicines, the educated doctor is able to home in on the cannabis based solution much sooner, perhaps saving the child's life.

 

The confusion is because I'm talking to someone who smokes weed who can't get is story straight.  You said Epidiolex, the cannabis based epilepsy drug, SEEMS to reduce seizures dramatically. It SEEMS like the is just one of the dozen epilepsy meds that needs to be tried that could save the child's life not THE med that will save the child's life.  

[McGee Return TD]

2 hours ago, row_33 said:

 

maybe smoke up and all my troubles go away

 

for a few minutes

 

alright McGee, you'll get your next spelling error with 100 of these attached to it, should be happening very very shortly.... 

 

 

 

Not if you block me first. 

35 minutes ago, Chef Jim said:

 

That's what I did.  Then the weed did absolutely nothing.  I met with a neurosurgeon who fixed the problem. Pain free since. 

 

The confusion is because I'm talking to someone who smokes weed who can't get is story straight.  You said Epidiolex, the cannabis based epilepsy drug, SEEMS to reduce seizures dramatically. It SEEMS like the is just one of the dozen epilepsy meds that needs to be tried that could save the child's life not THE med that will save the child's life.  

 

Bob's wrong. The FDA doesn't let a drug go to market if the only evidence is SEEMS. It is one of a few medications that can be used to treat patient's with, not epilepsy, but seizures due to two specific diagnoses. 

 

If you truly are interested, it's easy to find clinical trial information on the medication. 

[3rdnlng]

52 minutes ago, Chef Jim said:

 

That's what I did.  Then the weed did absolutely nothing.  I met with a neurosurgeon who fixed the problem. Pain free since. 

 

The confusion is because I'm talking to someone who smokes weed who can't get is story straight.  You said Epidiolex, the cannabis based epilepsy drug, SEEMS to reduce seizures dramatically. It SEEMS like the is just one of the dozen epilepsy meds that needs to be tried that could save the child's life not THE med that will save the child's life.  

So, it's true that a lobotomy is better than weed?

[Chef Jim]

2 minutes ago, 3rdnlng said:

So, it's true that a lobotomy is better than weed?

 

I don't know.  I've only smoked weed.  

[Bob in Mich]

1 hour ago, Chef Jim said:

 

That's what I did.  Then the weed did absolutely nothing.  I met with a neurosurgeon who fixed the problem. Pain free since. 

 

The confusion is because I'm talking to someone who smokes weed who can't get is story straight.  You said Epidiolex, the cannabis based epilepsy drug, SEEMS to reduce seizures dramatically. It SEEMS like the is just one of the dozen epilepsy meds that needs to be tried that could save the child's life not THE med that will save the child's life.  

 

If you weren't so certain that my answers must be f'd up because you know, cannabis, you might see that my answers have been perfectly sensible.  Intentionally or not, you seem stoned as you are unable or unwilling to comprehend today.

 

McGee is right, my answer was overly simplistic and so incorrect.  Epidiolex has so far been approved to treat two specific seizure disorders.  Forgive me please as I was trying to make the point about an educated versus uneducated doctor and didn't want to get overly detailed about various seizure disorders.

 

Back to the original discussion.....Have you seen the CNN special Weed, centering around Charlotte Figi?  Charlotte has Dravet Syndrome, one of the two conditions now treated with Epidiolex.  She was having over 100 seizures every day.  Her parents, as a last resort, tried treating her with cannabis concentrates.  They got very lucky and stumbled upon cannabis concentrates made with high CBD strains.  It was effective and reduced the kid's seizure count down to 1 or so a week.

 

Prior to Epidiolex, most treatment options for Dravet's were largely unsatisfactory.  They did not use cannabinoids.  Patients with this condition often did not live for very many years as the seizures were largely uncontrolled.  Today, a doctor educated in the endocannabinoid system, will know Epidiolex addresses the root cause of this illness.  Rather than taking a hit or miss approach with other seizure treatments, the educated physician can today pinpoint the cause as cannabinoid related.  A doctor unaware of the endocannabinoid system may still cling to the traditional anti-seizure medicines.

Edited June 6, 2019 by Bob in Mich