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UB says not so fast with this CTE stuff


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28 minutes ago, LeGOATski said:

There are plenty of players out there who are perfectly fine.

 

Smashing into things head-first is obviously bad for your brain.

 

I think I've just summed up everything the scientists know.

 

There's actually a bit more than that.  There are an increasing number of studies suggesting that amyloid beta has a role as an antiviral system in the brain.  In animal models, cells infected with viruses dramatically increase amyloid beta production.  Viruses provoking this response include herpes, CMV, Epstein Barr etc.  There may also be drug interactions. 

 

Smashing into things head-first while taking various drugs/supplements and/or being infected with certain viruses may be worse for your brain.

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3 hours ago, bbb said:

UB study of ex-Bills, Sabres finds CTE 'much more rare than we thought'

 

https://buffalonews.com/2018/08/07/ub-researchers-no-signs-of-early-onset-dementia-in-21-former-bills-and-sabres/

 

“In time, people will begin to realize it’s an important issue, CTE exists, but it’s much more rare than we thought,” Willer said.

 

sweet let's crack heads again.

 

 

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4 hours ago, Hapless Bills Fan said:

 

There's actually a bit more than that.  There are an increasing number of studies suggesting that amyloid beta has a role as an antiviral system in the brain.  In animal models, cells infected with viruses dramatically increase amyloid beta production.  Viruses provoking this response include herpes, CMV, Epstein Barr etc.  There may also be drug interactions. 

 

Smashing into things head-first while taking various drugs/supplements and/or being infected with certain viruses may be worse for your brain.

 

they're even linking viruses to alzheimers.

 

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6 hours ago, LeGOATski said:

There are plenty of players out there who are perfectly fine.

 

Smashing into things head-first is obviously bad for your brain.

 

I think I've just summed up everything the scientists know.

 

They want to ignore the effects of boxing, can’t combine that with football injuries, football is too holy or something.

 

 

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5 hours ago, Hapless Bills Fan said:

 

There's actually a bit more than that.  There are an increasing number of studies suggesting that amyloid beta has a role as an antiviral system in the brain.  In animal models, cells infected with viruses dramatically increase amyloid beta production.  Viruses provoking this response include herpes, CMV, Epstein Barr etc.  There may also be drug interactions. 

 

Smashing into things head-first while taking various drugs/supplements and/or being infected with certain viruses may be worse for your brain.

 

Could explain why the massive increases in CTE cases among NFL players coincided with the steroid era.  

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While I think this is (possibly) great news that it's not nearly as common as we thought....

 

Haven't we been told over and over that the only way to confirm CTE was for the person to be dead and you have to actually examine the brain? How the hell did they do a study with LIVING people, and go, "whelp, no CTE!"

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5 minutes ago, aristocrat said:

Just like the guy in Toronto who had severe cte but never played sports. They can’t figure it out

 

People get lung cancer without smoking, so light em up.

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7 hours ago, bbb said:

UB study of ex-Bills, Sabres finds CTE 'much more rare than we thought'

 

https://buffalonews.com/2018/08/07/ub-researchers-no-signs-of-early-onset-dementia-in-21-former-bills-and-sabres/

 

“In time, people will begin to realize it’s an important issue, CTE exists, but it’s much more rare than we thought,” Willer said.

 

Not surprising in the least.  The issue with most current studies published is that the donated brains were from people suffering from CTE at the time of death.  Duh - of course they are going to find CTE - so they naturally assumed that the concussions were the cause.

 

What more and more studies are finding is that it is not concussions that cause the issue - especially as they study more players that had concussions, but are not affected (the majority of players).  They also find CTE in people that had did not play sports and had no known history of concussions.  So there was always more to the story.  That is why the shift about 2 years ago from concussions being the big culprit to repeatedly being struck in the head.  Lots of little injuries, but that has not panned out either.

 

I believe they will find something genetic in the end that makes certain players more susceptible (similar to the narrowing of the spinal column that caused paralysis for some players) and that combined with both the physical toll (oxygen depletion- banging of the brain - etc.) increases the risk factors.

 

I will not argue that concussions and repeatedly getting blows to the head are bad for you long term and may have some impact, but I have always thought it stupid that a big deal has been made that in people with suspected CTE that donated their brains and CTE was found - they made assumptions with no control groups, no studies of brains in healthy football players, no studies of CTE brains in non-athletes, nothing to make it scientific and provide real insight.

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9 minutes ago, Kemp said:

 

People get lung cancer without smoking, so light em up.

There is more than one kind of lung cancer. Adenocarcinoma may be found in non-smokers. Even still most adenocarcinoma of the lung is associated with smoking and there is a very strong connection between squamous cell and small cell cancer.

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24 minutes ago, aristocrat said:

Just like the guy in Toronto who had severe cte but never played sports. They can’t figure it out

Ha!  Until the 2017-18 season, it was from bashing his head against a brick wall over the futility of Leafs hockey.  Maybe this study should be done on rabid fans of underachieving sports franchises.

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24 minutes ago, CLTbills said:

While I think this is (possibly) great news that it's not nearly as common as we thought....

 

Haven't we been told over and over that the only way to confirm CTE was for the person to be dead and you have to actually examine the brain? How the hell did they do a study with LIVING people, and go, "whelp, no CTE!"

 

They are finding more blood markers and in this case evidence from brain scans - where the damage occurs to determine dementia and onset of CTE.

 

This is the third such study that is finding that it is not concussions as much as potentially brain injury combined with other factors that leads to CTE.  These studies are much more scientific in nature not just looking at known CTE people, but “healthy” players with no issues.

 

I think long term - concussions will be linked to some of the mood swings and memory loss players experience depending on what part of the brain gets bruised and injuried.  It is obvious that getting lit up and suffering a concussion is bad, but it may not be the driver to CTE it was touted to be years ago.

 

I can’t wait to see more studies on this from both sides.  More research was always needed.

 

 

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