Seantrel Henderson suspended another 10 games

[Mr. WEO]

Yeah, I'm sure following the rules is the first thing on your mind when your Dr. says something could help you avoid losing even more of your intestines.

 

His door did not tell him to smoke weed.

 

there are times when you have to separate and distinguish between humanity and football. Crohn's is a very serious disease. Its to the point with this guy where he is going to have to unfortunately choose between football and his health, bc theres no doubt marijuana is an effective treatment for the disease.

 

http://www.medicaldaily.com/medical-marijuana-achieves-complete-remission-crohns-disease-drug-improves-247783

 

https://www.google.com/amp/s/amp.cnn.com/cnn/2015/04/15/health/marijuana-medical-advances/index.html?client=safari

 

https://www.ncbi.nlm.nih.gov/m/pubmed/23648372/

 

He should probably just retire.

 

 

Don't conuse us with facts, we can't handle that here.

 

This nonsense will never end. You are so misinformed.

 

Smoking marijuana is simply not the standard of care for this disease. Even though you provide links, they still only state 1 trial including only 11 patients. People want to call it a success, they did not meet their primary end-point of the study (which was inducing remission) was not met. And this was why it was publish in an obscure journal.

 

There's still years to go before claiming there's a significant clinical benefit, but to say he did it at the urging of his doctor is pure horse ****.

 

I am a physician and have lived with Crohn's since I was 15, including have had a total colectomy. This argument of marijuana being beneficial for Crohn's is anecdotal at best. Frankly, I think he's full of ****.

 

Thank you Saint Doug. I never imagined we could have a physician who also has Crohn's to put this nonsense to rest. I have treated Crohn's surgically not medically, but not one patient I have operated on was treated with any form of cannabis. As you say, it simply does not exist as a primary or secondary treatment for his disease.

 

Henderson is smoking weed because he wants to not because he has to. This argument is over. Listen to Saint Doug.

[Fingon]

I'd like to hear about some studies that don't show that medical marijuana helps people with Crohn's.

 

 

RESULTS:

Of the 30 patients 21 improved significantly after treatment with cannabis. The average Harvey Bradshaw index improved from 14 +/- 6.7 to 7 +/- 4.7 (P < 0.001). The need for other medication was significantly reduced. Fifteen of the patients had 19 surgeries during an average period of 9 years before cannabis use, but only 2 required surgery during an average period of 3 years of cannabis use.

CONCLUSIONS:

This is the first report of cannabis use in Crohn's disease in humans. The results indicate that cannabis may have a positive effect on disease activity, as reflected by reduction in disease activity index and in the need for other drugs and surgery. Prospective placebo-controlled studies are warranted to fully evaluate the efficacy and side effects of cannabis in CD.

https://www.ncbi.nlm.nih.gov/pubmed/21910367

I'd keep posting evidence, but the response is just "Nuh uh only 30 people in the study."

[North Buffalo]

I thinks there's something to the use of marijuana to deal with the pain of cancer. While marijuana is not an analgesic itself, it is anxiolytic, which can help ease the psychological stress of pain. There are some articles out there about THC receptors not only being present in the central nervous system, but also on white blood cells, where they *may* modulate immune function.

 

But, at this point in time, I just don't see any legitimate gastroenterologist urging their patient to smoke marijuana, especially when they know it's going to lead to an automatic suspension. A good doctor would search for appropriate alternatives. Although different, smoking tobacco can really worsen a patient's Crohn's. While marijuana is not tobacco, the point is smoking marijuana could even be harmful for Crohn's, we just don't know and need much more data before labeling it "beneficial".

Thanks for your input Doc. I work as an X-Ray, CT Tech and see a lot of folks judging others before they know anything about their diseases....

 

My mother dealt with post-polio syndrome by using vodka maintenance rather than take Valium... not saying it was the great that she was a maintenance drinker... but given the medical alternative at the time... it was better that what was available....

 

Look at all the OXY addicts out there and tell me that the prescriptions given out are appropriate.... Medical industry is just as full of it.

 

I just got pissed when I saw all the judgmentalism being used by know nothings.

[Fingon]

I thinks there's something to the use of marijuana to deal with the pain of cancer. While marijuana is not an analgesic itself, it is anxiolytic, which can help ease the psychological stress of pain. There are some articles out there about THC receptors not only being present in the central nervous system, but also on white blood cells, where they *may* modulate immune function.

 

But, at this point in time, I just don't see any legitimate gastroenterologist urging their patient to smoke marijuana, especially when they know it's going to lead to an automatic suspension. A good doctor would search for appropriate alternatives. Although different, smoking tobacco can really worsen a patient's Crohn's. While marijuana is not tobacco, the point is smoking marijuana could even be harmful for Crohn's, we just don't know and need much more data before labeling it "beneficial".

Here's the list of studies that show medical marijuana doesn't help Crohn's:

 

 

 

 

 

 

 

 

 

[BADOLBILZ]

 

Rarely agree with BADOL but I do this time - it is their union and if it is not doing the best for the members it is time to dissolve it and form new one.

 

The NFLPA spends a lot of money defending those who break rules and those players who hurt other players. It has opposed mandatory safety equipment.

 

The NFLPA's goal is like an agent - attempting to get highest percentage since it is union's best interest not necessarily players.

 

They could try to hold out on issue but the players who do not have interest in this may not agree with lower percentage for that 'benefit'; same thing for getting "No Fun League" to allow players to act like clowns - all players may not agree with lower percentage for that. They need to prioritize what they want and realize this is a zero sum game and will need to give up something to get something. The NFLPA got a lot of restrictions on preseason and off season work which has caused a decrease in the quality of the game. If they wish less preseason game they will need to agree with more regular games; if they worked with NFL they could get longer schedule with more bye weeks and more recovery time in season but NFLPA is not a partner of NFL despite words.

 

It is not legal in ANY city - some cities/states will not prosecute but it is still federal crime and drug policy is determined by federal government despite wishes of pro pot advocates.

 

Well said. It bothers me that the players don't have safer pain relief options......but it's hard to get too exercised about an effect they aren't committed to change.

 

What bothers me more as a consumer of the league product is the fact that we have to wait what seems like further into every season each year for teams to start playing good, organized NFL football.

 

That is depriving us fans of a better product. That is something we should be upset about. The teams are rounding into form now but half of this NFL season was very hard to watch. This is a fan problem. Not players needing MJ.

[Mr. WEO]

I'd like to hear about some studies that don't show that medical marijuana helps people with Crohn's.

 

 

RESULTS:

Of the 30 patients 21 improved significantly after treatment with cannabis. The average Harvey Bradshaw index improved from 14 +/- 6.7 to 7 +/- 4.7 (P < 0.001). The need for other medication was significantly reduced. Fifteen of the patients had 19 surgeries during an average period of 9 years before cannabis use, but only 2 required surgery during an average period of 3 years of cannabis use.

CONCLUSIONS:

This is the first report of cannabis use in Crohn's disease in humans. The results indicate that cannabis may have a positive effect on disease activity, as reflected by reduction in disease activity index and in the need for other drugs and surgery. Prospective placebo-controlled studies are warranted to fully evaluate the efficacy and side effects of cannabis in CD.

https://www.ncbi.nlm.nih.gov/pubmed/21910367

I'd keep posting evidence, but the response is just "Nuh uh only 30 people in the study."

 

 

You keep proving that you don't understand how results of clinical trials are implemented and how tries themselves are performed.

 

You need to quit while you are way way behind. Turn off your google. It's not helping you.

Edited November 25, 2016 by Mr. WEO

[Fingon]

 

 

You keep proving that you don't understand how results of clinical trials are implemented and how tries themselves are performed.

 

You need to quit while you are way way behind. Turn off your google. It's not helping you.

"Nuh uh you're wrong"

Lets see ANYTHING that contradicts these studies.

Evidence against marijuana helping people with crohn's:

 

 

 

 

Oh wait, there isn't any.

Oh wait, here's more:

 

This is the first clinical trial on the effect of Cannabis in IBD and it confirms what has been suggested for a long time from experimental studies, namely that cannabinoids may provide antiinflammatory effects and symptomatic benefit in patients with IBD. The physiological fundament for the beneficial effects of Cannabis has been established a while ago and unraveled since then. The discovery of cannabinoid receptors and endogenous molecules activating these receptors led to the description of a coordinated network that is inherent to the mammalian organism, the so-called endocannabinoid system. This system consists of the canonical CB receptors (cannabinoid receptor 1 and 2; CB1, CB2), their endogeneous ligands anandamide and 2-arachidonoyl glycerol (2-AG), also called endocannabinoids, and their synthesizing and degrading enzymes. What capsaicin, the pungent ingredient of chili, is for vanilloid receptors and morphin for opioid receptors, is tetrahydrocannabinol (THC), the psychodelic ingredient of Cannabis, for cannabinoid (CB) receptors: the predominant herbal ligand. Thus, THC mimics the actions of anandamide and 2-AG.

 

 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076530/

 

 

Still waiting on a single study that contradicts any that I have posted. Come on guys, I know you can do it. I'll be over here while the evidence piles up that cannabis does help those with crohn's.

Edited November 25, 2016 by Fingon

[Mr. WEO]

"Nuh uh you're wrong"

Lets see ANYTHING that contradicts these studies.

Evidence against marijuana helping people with crohn's:

 

 

 

 

Oh wait, there isn't any.

Oh wait, here's more:

 

This is the first clinical trial on the effect of Cannabis in IBD and it confirms what has been suggested for a long time from experimental studies, namely that cannabinoids may provide antiinflammatory effects and symptomatic benefit in patients with IBD. The physiological fundament for the beneficial effects of Cannabis has been established a while ago and unraveled since then. The discovery of cannabinoid receptors and endogenous molecules activating these receptors led to the description of a coordinated network that is inherent to the mammalian organism, the so-called endocannabinoid system. This system consists of the canonical CB receptors (cannabinoid receptor 1 and 2; CB1, CB2), their endogeneous ligands anandamide and 2-arachidonoyl glycerol (2-AG), also called endocannabinoids, and their synthesizing and degrading enzymes. What capsaicin, the pungent ingredient of chili, is for vanilloid receptors and morphin for opioid receptors, is tetrahydrocannabinol (THC), the psychodelic ingredient of Cannabis, for cannabinoid (CB) receptors: the predominant herbal ligand. Thus, THC mimics the actions of anandamide and 2-AG.

 

 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076530/

 

 

Still waiting on a single study that contradicts any that I have posted.

 

Where are the prospective placebo controlled doubt blinded studies that show cannabis is an effective treatment for Crohn's disease? That's how treatment decisions are actually made in medicine as a standard. Every study you cite calls for such further study.

 

There are none, hence no reputable IBD treatment centers have abandoned current therapy regimens in favor of whatever it is you are talking about.

Edited November 25, 2016 by Mr. WEO

[Fingon]

 

Where are the prospective placebo controlled doubt blinded studies that show cannabis is an effective treatment for Crohn's disease? That's how treatment decisions are actually made in medicine as a standard.

 

There are none, hence no reputable IBD treatment centers have abandoned current therapy regimens in favor of whatever it is you are talking about.

"Nuh uh, you're wrong"

 

I also think you mean double blind, and they're over in some pile waiting for the DEA to approve them. Small clinical trials point you in a direction for further study. It just so happens these small clinical trials line up with what the pharmacology says they should do. You can say that marijuana doesn't help with crohn's but the studies and pharmacology available say you are wrong.

[Mr. WEO]

"Nuh uh, you're wrong"

 

I also think you mean double blind, and they're over in some pile waiting for the DEA to approve them. Small clinical trials point you in a direction for further study. It just so happens these small clinical trials line up with what the pharmacology says they should do. You can say that marijuana doesn't help with crohn's but the studies and pharmacology available say you are wrong.

 

It's not me who says you are wrong. Go ask any leading Crohn's specialists in this country and ask how many of them have their patients smoking weed as part of the acute or maintenance portion of their treatment.

 

And guess who's doctor didn't prescribe weed to treat his patient's Crohn's (now in surgical remission) disease?

[Kirby Jackson]

This one is tricky for me and an interesting test case. Medical Marijuana has been an effective treatment for Crohn's disease and is legal in many states. At the same time the league bans it and NY isn't one of those states. I certainly don't think that the NFL gains anything by testing for marijuana but it is the rule. I don't really have a strong opinion one way or another but think that the situation is unfortunate any way that you look at it.

[Mr. WEO]

This one is tricky for me and an interesting test case. Medical Marijuana has been an effective treatment for Crohn's disease and is legal in many states. At the same time the league bans it and NY isn't one of those states. I certainly don't think that the NFL gains anything by testing for marijuana but it is the rule. I don't really have a strong opinion one way or another but think that the situation is unfortunate any way that you look at it.

 

 

If smoking MJ was the standard of care in Crohn's therapy, there would be, maybe, an argument to made here for an exemption.

 

But it's not and it's certainly likely his doctor didn't tell him to smoke. He's been doing it for years. In fact the vast majority Crohn's patients are adequately treated without weed. In fact, since his doctor would know this, he would be especially careful to avoid having his patient take a banned substance with unproven benefit.

 

It would make no sense in any way.

[Fingon]

 

 

If smoking MJ was the standard of care in Crohn's therapy, there would be, maybe, an argument to made here for an exemption.

 

But it's not and it's certainly likely his doctor didn't tell him to smoke. He's been doing it for years. In fact the vast majority Crohn's patients are adequately treated without weed. In fact, since his doctor would know this, he would be especially careful to avoid having his patient take a banned substance with unproven benefit.

 

It would make no sense in any way.

Whew lad! Another one:

 

RESULTS:

Thirteen patients were included. After 3 months' treatment, patients reported improvement in general health perception (p = 0.001), social functioning (p = 0.0002), ability to work (p = 0.0005), physical pain (p = 0.004) and depression (p = 0.007). A schematic scale of health perception showed an improved score from 4.1 ± 1.43 to 7 ± 1.42 (p = 0.0002). Patients had a weight gain of 4.3 ± 2 kg during treatment (range 2-8; p = 0.0002) and an average rise in BMI of 1.4 ± 0.61 (range 0.8-2.7; p = 0.002). The average Harvey-Bradshaw index was reduced from 11.36 ± 3.17 to 5.72 ± 2.68 (p = 0.001).

CONCLUSIONS:

Three months' treatment with inhaled cannabis improves quality of life measurements, disease activity index, and causes weight gain and rise in BMI in long-standing IBD patients.

https://www.ncbi.nlm.nih.gov/pubmed/22095142

Still waiting on anything that contradicts any of this.

Oh, and :

:

A comparable proportion of UC and CD patients reported lifetime [48/95 (51%) UC vs. 91/189 (48%) CD] or current [11/95 (12%) UC vs. 30/189 (16%) CD] cannabis use. Of lifetime users, 14/43 (33%) UC and 40/80 (50%) CD patients have used it to relieve IBD-related symptoms, including abdominal pain, diarrhoea and reduced appetite. Patients were more likely to use cannabis for symptom relief if they had a history of abdominal surgery [29/48 (60%) vs. 24/74 (32%); P=0.002], chronic analgesic use [29/41 (71%) vs. 25/81 (31%); P<0.001], complimentary alternative medicine use [36/66 (55%) vs. 18/56 (32%); P=0.01] and a lower short inflammatory bowel disease questionnaire score (45.1±2.1 vs. 50.3±1.5; P=0.03). Patients who had used cannabis [60/139 (43%)] were more likely than nonusers [13/133 (10%); P<0.001 vs. users] to express an interest in participating in a hypothetical therapeutic trial of cannabis for IBD.

CONCLUSION:

Cannabis use is common amongst patients with IBD for symptom relief, particularly amongst those with a history of abdominal surgery, chronic abdominal pain and/or a low quality of life index. The therapeutic benefits of cannabinoid derivatives in IBD may warrant further exploration.

Turns out about half of those that suffer from IBD are lifetime users of marijuana. Doesn't seem like the vast majority get by without it to me.

https://www.ncbi.nlm.nih.gov/pubmed/21795981

[Dr.Sack]

I prefer hybrid cannabis. A good strain is AC/DC which is about 4.5% THC and over 9% CBD, you get a great high very little psychoactive effects and a good full body numbness.

[Mr. WEO]

Whew lad! Another one:

 

RESULTS:

Thirteen patients were included. After 3 months' treatment, patients reported improvement in general health perception (p = 0.001), social functioning (p = 0.0002), ability to work (p = 0.0005), physical pain (p = 0.004) and depression (p = 0.007). A schematic scale of health perception showed an improved score from 4.1 ± 1.43 to 7 ± 1.42 (p = 0.0002). Patients had a weight gain of 4.3 ± 2 kg during treatment (range 2-8; p = 0.0002) and an average rise in BMI of 1.4 ± 0.61 (range 0.8-2.7; p = 0.002). The average Harvey-Bradshaw index was reduced from 11.36 ± 3.17 to 5.72 ± 2.68 (p = 0.001).

CONCLUSIONS:

Three months' treatment with inhaled cannabis improves quality of life measurements, disease activity index, and causes weight gain and rise in BMI in long-standing IBD patients.

https://www.ncbi.nlm.nih.gov/pubmed/22095142

Still waiting on anything that contradicts any of this.

Oh, and :

:

A comparable proportion of UC and CD patients reported lifetime [48/95 (51%) UC vs. 91/189 (48%) CD] or current [11/95 (12%) UC vs. 30/189 (16%) CD] cannabis use. Of lifetime users, 14/43 (33%) UC and 40/80 (50%) CD patients have used it to relieve IBD-related symptoms, including abdominal pain, diarrhoea and reduced appetite. Patients were more likely to use cannabis for symptom relief if they had a history of abdominal surgery [29/48 (60%) vs. 24/74 (32%); P=0.002], chronic analgesic use [29/41 (71%) vs. 25/81 (31%); P<0.001], complimentary alternative medicine use [36/66 (55%) vs. 18/56 (32%); P=0.01] and a lower short inflammatory bowel disease questionnaire score (45.1±2.1 vs. 50.3±1.5; P=0.03). Patients who had used cannabis [60/139 (43%)] were more likely than nonusers [13/133 (10%); P<0.001 vs. users] to express an interest in participating in a hypothetical therapeutic trial of cannabis for IBD.

CONCLUSION:

Cannabis use is common amongst patients with IBD for symptom relief, particularly amongst those with a history of abdominal surgery, chronic abdominal pain and/or a low quality of life index. The therapeutic benefits of cannabinoid derivatives in IBD may warrant further exploration.

Turns out about half of those that suffer from IBD are lifetime users of marijuana. Doesn't seem like the vast majority get by without it to me.

https://www.ncbi.nlm.nih.gov/pubmed/21795981

 

 

Euphoria is very pleasant. It's not a wonder that patients of many chronic diseases may self medicate with MJ--especially in states such as California, where weed has been legal for decades. That's not news. It's not even worth "studying" (it was a survey).

 

Nothing you cite can refute the fact that this isn't standard therapy for this disease and that Henderson was self medicating, hence, he is suspended.

 

Keep going though.

[bobobonators]

Again, he should probably retire bc the rules are what they are. Im not sure if he applied for a medical exemption or if he didnt. Either way, i still think its important to keep the human aspect of this story in perspective. The guy has a serious struggle. And he doesnt have a sedentary job which further complicates matters.

 

To call the guy out as just another pothead or lazy is a tad unfair.

[bigK14094]

Lots of pain killers besides pot........not worth naming....but, get a script if you need it. Say, Tramadol........

[Doc]

Perhaps pot is helping Seantrel with his Crohn's. But the reality is the NFL doesn't care and he'll continue to be suspended if he continues to use it. He needs to step away and decide whether he wants to keep treating the condition with pot or play in the NFL without it.

[NoSaint]

Perhaps pot is helping Seantrel with his Crohn's. But the reality is the NFL doesn't care and he'll continue to be suspended if he continues to use it. He needs to step away and decide whether he wants to keep treating the condition with pot or play in the NFL without it.

Or coast into forced retirement collecting as much cash as he can along the way (which may be the current situation)

[Chandemonium]

https://www.ncbi.nlm.nih.gov/pubmed/23648372

RESULTS:

Complete remission (CDAI score, <150) was achieved by 5 of 11 subjects in the cannabis group (45%) and 1 of 10 in the placebo group (10%; P = .43). A clinical response (decrease in CDAI score of >100) was observed in 10 of 11 subjects in the cannabis group (90%; from 330 ± 105 to 152 ± 109) and 4 of 10 in the placebo group (40%; from 373 ± 94 to 306 ± 143; P = .028). Three patients in the cannabis group were weaned from steroid dependency. Subjects receiving cannabis reported improved appetite and sleep, with no significant side effects. CONCLUSIONS:

Although the primary end point of the study (induction of remission) was not achieved, a short course (8 weeks) of THC-rich cannabis produced significant clinical, steroid-free benefits to 10 of 11 patients with active Crohn's disease, compared with placebo, without side effects. Further studies, with larger patient groups and a nonsmoking mode of intake, are warranted.

Improved appetite and sleep huh? Who would've thought?