I assume this question is coming from musing about how the Bills D might play Miami and Tyreek Hill. Yes, NFL defenses will sometimes lock a premier CB (say Darell Revis) on the opponent’s best WR and play man /zone with the rest depending on the call. But who could the Bills possibly put on Hill that would have any hope of staying with him 1v1? Honestly, that goes for Waddle as well.
Belichick, as mentioned above, is well know for putting his best CB on the opponent’s second best WR and then bracketing the best one with two players. But the bills have never done this, as far as I’m aware, so I’d be expecting a variety of zones on Sunday.