I think this becomes more of a debate if the scenario is that the player is a guaranteed HOFer.
In that case, if there was a QB already in place, I would be tempted to say yes. You never know how a late 1st round pick is going to pan out. Sure, one of the two might be a good starter, but a HOFer is a game changer at his position.
I'd probably do it for almost any position, especially WR, LT, DT, DE, MLB, and CB, so long as they are a HOFer for insane production.