As I'm sure you know, the Lions and Bills have been connected since even before the Bills were founded. I'm actively rooting for the Lions after the Bills, FWIW, and I'm sure I'm not alone.
He suggests the Bills are at a "supreme disadvantage" and have the worst health of all remaining playoff teams:
https://sicscore.com/nfl/updates/kansas-city-chiefs-vs-buffalo-bills-which-team-has-the-injury-edge