I use Quicken and love it -- but don't love that they force you to buy a new version every 2 years.
MS Money does the same thing.
If you think that you can use a spreadsheet, then you're not using the full power of the software. Quicken (and Money) integrate with financial institutions so you can literally click a button and download all of your transactions. Very simple.
You can also use it to track spending on certain categories - for example, how much did you spend eating out for lunch over the past 3 months compared to the same period last year? Stuff like that.
I'm a huge fan - and track everything with it, including money that travels in and out of my wallet. I'm a bit fanatical, but I love being able to see where every penny goes and it helps you curtail your spending by identifying waste.
It's had a few bugs here and there, but overall it's been relatively stable. That said, I would've been happy to still be using the 2002 version.