They have been a top3 unit three out of the last 4 years playing all kinds of teams, good mediocre and bad, with largely the same core pieces. It’s a really, really good defense.
Very unlikely imo. The Bills have the best defense in terms of net yards/attempt in the league by quite a bit, and Tua is 24th in terms of YPA or thereabouts.
There just won’t be enough opportunities for him vs this defense. He’s not able to create enough on his own to really stress coverages and the Phin’s don’t have enough weapons to exploit Frazier’s zone.