Always look at matchups and here is my preliminary take on it (have only watched bits of the Dolphins game so going with some stats):
Bills on O:
+ Bills WR > Dolphins secondary
+/- EJ looked good so last game but had nice pocket to work from. Not sure how he will do with smaller and collapsing pocket
+/- Bills RB vs LB: With our variety at RBs, Bills have the edge but their LBs are very good too.
+/- Bills OL vs Dolphins DL: This holds the key to the game. If our tackles hold and Wood controls the line, we will win
Dolphins likely will come with man coverage and pressure off the edges. if tackles hold up and we can set up screens/ crossing routes, Bills will do fine. Chandler, Watkins should
Bills on D:
+ Bills DBs vs WRs: Wallace, Hartline are good and will be a handful. After a decent performance against the Bears WRs, I see Bills holding the advantage
+/- Moreno vs LBs: Moreno had a good game but Spikes is on fire, we get Bradham back.
+ Tannehill vs DL and DB: I think Tannehill will see a lot of pressure from the front 4 and their OL isn't suited to hold up against this constant pressure
- Bills penalties: have to get these under control. There were some bad calls on Sunday, but going back to last year the inopportune penalties were driving me nuts.
Bills have HF advantage also. If Bills can be disciplined and not over-anxious, Bills should have the edge