Completely depends on Foles
The Eagles have a good defense for Tom Brady. They get pressure rushing 4 and have a decent secondary that can cover long enough for that 4 to get to the QB.
The offense should do better than the Jags did.
Theoretically they should be able to win but with Bill Belichick able to plan for 2 weeks, it's on Foles to perform. If he lays an egg, they will get destroyed.