I think a lot of the VALID concern about running up the gut on 2nd and 10 MAY also have a valid rebuttal. You are up against what may be the most beastly front four you'll face all season, and they are all capable penetrators. Cook is slippery, and seems capable of wriggling between DTs, like it's his job (because it is...).
We all piss and moan about the long home-run carries popped off against us, but it's almost never more than one per game.
Think about the psychology of it, from Washington's side: Why would the Bills run up the gut on 2nd and 10? It's unexpected. They'll stop doing it.
Bills side: If just one of these works, it's 6 points and a cloud of dust.