The problem is that the Bills have zero Guards or TEs who have shown any propensity to get out into space and block people.
You're just not going ot have a successful screen game with that kind of personnel.
You might pop one every once in a rare while or run a few just to give the pass rush something to think about (which I am all for in certain matchups), but it's not something this team can use with any sort of regularity this year.