Sure! It's unlikely given the Bills have a Top 3 QB and a Top 5 overall organization, so may is doing a lot of heavy lifting, but it's possible. I think it's extremely plausible he could end up Top 12, a la Stroud. Not likely, but plausible.
In terms of likeliness, I think the Bills' WR talent comes in around #16 (one of Coleman or Claypool is productive), #28 (neither is productive), #12 (both are productive). I think middle of the pack would be a net improvement over back-half Diggs and Davis last season.