Probably not. It's very rare that Chicago is this good late in the season & Green Bay has a national following too. The only other FOX top 10 tv markets with teams playing at 1 are Atlanta & DC, so Bills/Bengals will likely be a good lead-in for most of the country.
The local Buffalo affiliates aren't happy though. CBS will have to air Broncos-Raiders at 4 (instead of likely Steelers/Ravens @ 1) & FOX will have a slightly smaller (but still massive) number at 1 instead of 425.