Such a weird year being the first time they can carry this many players into the final week. I don't understand it at all. Seems like a lose lose for teams and players. I think they know who their top 42 maybe 45 players are.
This may seem odd, but I would cut players 65-75 now. They have no hope of making the team. Let players 75-90 play against the Lions taking up the bulk of the snaps with the seconds and thirds. That opens up ten roster spots to make some moves.
I would cut Ducasse, a few DB's, a safety, IR settlement Yates, IR Streeter, trade Ragland, and cut one DE. That is 8 players right there.