billsfanmiamioh Posted August 31, 2023 Share Posted August 31, 2023 9 hours ago, ExiledInIllinois said: And what happens if these studies comeback negative... Like the link between schizophrenia and cannabis use with an at risk population https://pubmed.ncbi.nlm.nih.gov/32839678/ Not trying to be solely negative... It's just that we need to be able to handle the unintended consequences, NOT flip the script. There are unintended consequences and side effects for everything that we put into our bodies, and cannabis is no different. It absolutely has therapeutic value and it absolutely has real risks. That’s why any clinician that’s worth their salt has evaluated their patient on a personal level to identify potential risks of cannabis use that would be higher for that particular person based on their health history. That study you referenced is a systematic review, which can be a powerful evaluation but for cannabis studies usually isn’t, due to the heterogeneity and limits of the included studies (crap in, crap out). There does appear to be a link between cannabis use and schizophrenia in a subset of the population with certain risk factors, but at this point most scientists would not say it’s not causal. More studies with proper designs and larger sample sizes are needed to explore this more. Cannabis is not an appropriate medicinal treatment for everyone. But it should be treated like any other drug where risks and benefits are discussed then the patient is monitored for changes in behavior and baseline health measures I’d argue that most RX drugs that get prescribed to people aren’t properly evaluated for use in that person because they’ve undergone extensive FDA testing and approval, so they are considered “safe”. This has been limited for cannabis drugs due to the barriers in performing research and it’s been stuck in a weird catch 22 type loop for decades And yes, most likely “highly” influenced by big pharma (pun intended). Adult use (recreational) cannabis use presents different considerations. I could go on for days with this stuff but overall at this point I believe it should be treated like alcohol. And I strongly believe that it’s important for states to have both medical and adult use cannabis programs, as it’s not all the same. 2 Quote Link to comment Share on other sites More sharing options...
ExiledInIllinois Posted August 31, 2023 Share Posted August 31, 2023 12 minutes ago, billsfanmiamioh said: There are unintended consequences and side effects for everything that we put into our bodies, and cannabis is no different. It absolutely has therapeutic value and it absolutely has real risks. That’s why any clinician that’s worth their salt has evaluated their patient on a personal level to identify potential risks of cannabis use that would be higher for that particular person based on their health history. That study you referenced is a systematic review, which can be a powerful evaluation but for cannabis studies usually isn’t, due to the heterogeneity and limits of the included studies (crap in, crap out). There does appear to be a link between cannabis use and schizophrenia in a subset of the population with certain risk factors, but at this point most scientists would not say it’s not causal. More studies with proper designs and larger sample sizes are needed to explore this more. Cannabis is not an appropriate medicinal treatment for everyone. But it should be treated like any other drug where risks and benefits are discussed then the patient is monitored for changes in behavior and baseline health measures I’d argue that most RX drugs that get prescribed to people aren’t properly evaluated for use in that person because they’ve undergone extensive FDA testing and approval, so they are considered “safe”. This has been limited for cannabis drugs due to the barriers in performing research and it’s been stuck in a weird catch 22 type loop for decades And yes, most likely “highly” influenced by big pharma (pun intended). Adult use (recreational) cannabis use presents different considerations. I could go on for days with this stuff but overall at this point I believe it should be treated like alcohol. And I strongly believe that it’s important for states to have both medical and adult use cannabis programs, as it’s not all the same. Yeah... But let's not just flip the script. I get, people want it and should have access to it. Quote Link to comment Share on other sites More sharing options...
billsfanmiamioh Posted August 31, 2023 Share Posted August 31, 2023 11 minutes ago, ExiledInIllinois said: Yeah... But let's not just flip the script. I get, people want it and should have access to it. With all due respect wtf does that mean? 😂 Quote Link to comment Share on other sites More sharing options...
billsfanmiamioh Posted August 31, 2023 Share Posted August 31, 2023 7 hours ago, Miyagi-Do Karate said: This book really changed my mind on medical marijuana and legalization. Strong evidence linking marijuana use as causing mental health disorders. https://www.amazon.com/Tell-Your-Children-Marijuana-Violence/dp/1982103663 Didn’t see your post here. But I agree. It is really concerning if you read the literature. Also the THQ content in marijuana Today appears to be way higher than that of the 1960s. That’s simply not true and I’d be wary of basing opinions on cannabis off literature that cherry picks “studies”, mixes in anecdotal tales, and makes huge leaps in logic to attempt to establish some kind of causal relationship, only to sell this groundbreaking information in a book on Amazon instead of actually performing a structured systematic review or meta analysis. 1 1 Quote Link to comment Share on other sites More sharing options...
Not at the table Karlos Posted August 31, 2023 Share Posted August 31, 2023 (edited) 11 hours ago, GoBills808 said: You mean the cannabis plant, all by itself? If you truly believe there's medical value in a substance, wouldn't you want the professionals doing the cultivation/production of the medicine? In my experience the professionals get greedy and screw it up. I'd rather just go to my attic where I don't have to pay taxes. Edited August 31, 2023 by Not at the table Karlos Quote Link to comment Share on other sites More sharing options...
ExiledInIllinois Posted August 31, 2023 Share Posted August 31, 2023 27 minutes ago, billsfanmiamioh said: With all due respect wtf does that mean? 😂 Flip the script. Just reverse what policy was but in the end it's really the same, just a mirror image of what was previous. Repeat the same mistakes, keep the same arrogance, etc... NOT making REAL change. 21 minutes ago, billsfanmiamioh said: That’s simply not true and I’d be wary of basing opinions on cannabis off literature that cherry picks “studies”, mixes in anecdotal tales, and makes huge leaps in logic to attempt to establish some kind of causal relationship, only to sell this groundbreaking information in a book on Amazon instead of actually performing a structured systematic review or meta analysis. Just saying, got a million different people with a million different bodies. Sure we aren't opening up Pandora's Box? Are we making the same argument as say gun owners? I like them, I have a right, that's for other people to figure out how to handle it... Just don't take away my individual ability to obtain these things. I am not against... Just very cautious... Quote Link to comment Share on other sites More sharing options...
Bill from NYC Posted August 31, 2023 Share Posted August 31, 2023 21 minutes ago, Not at the table Karlos said: In my experience the professionals get greedy and screw it up. I'd rather just go to my attic where I don't have to pay taxes. I can't say that I blame you. I doubt if you are spraying pesticides up there, and your future seeds would appear to be at least somewhat more safe than those laced with pesticides. That said, I make no claim of being an expert. 1 Quote Link to comment Share on other sites More sharing options...
WhoTom Posted August 31, 2023 Share Posted August 31, 2023 3 hours ago, billsfanmiamioh said: That’s simply not true and I’d be wary of basing opinions on cannabis off literature that cherry picks “studies”, mixes in anecdotal tales, and makes huge leaps in logic to attempt to establish some kind of causal relationship, only to sell this groundbreaking information in a book on Amazon instead of actually performing a structured systematic review or meta analysis. Thank you. Book publishers are not peer reviewers. If they think a book will sell, they'll publish it. And controversy sells. Many years ago, my SIL convinced my in-laws to try a diet that's based on one's blood type. It was based on a book written by a medical doctor whose hypothesis was that blood types tend to be related to our places of ancestry, so our bodies are designed to eat the foods that come from those regions. A reasonable hypothesis, to be sure, and one that warranted further investigation. But he bypassed (or failed to get through) the peer review process and published the book. A couple of years later, he published another book acknowledging that it's not quite that simple, and then went into all kinds of variations on the diet, the rough equivalent of adding epicycles to the Ptolemaic (Earth-centered) model of the solar system. In physics class, we jokingly called this a fudge factor - a constant that makes the data match the hypothesis, even when it clearly doesn't. Scientific research is put through a rigorous peer review process to account for research biases, and extraneous variables, and to ensure good research practices. I take no medical advice from any source - books, internet message boards, randos in parking lots - unless it's supported by peer-reviewed research. 1 Quote Link to comment Share on other sites More sharing options...
GoBills808 Posted August 31, 2023 Share Posted August 31, 2023 4 hours ago, Not at the table Karlos said: In my experience the professionals get greedy and screw it up. I'd rather just go to my attic where I don't have to pay taxes. I've never understood that rhetoric when it comes to medicinal cannabis. I mean, nobody thinks it's hugely important we make our own aspirin or whatever Quote Link to comment Share on other sites More sharing options...
Rico Posted August 31, 2023 Share Posted August 31, 2023 Legal in MD since July. 1 edible isn’t enough, 3 edibles are too much, 2 edibles are just right. Quote Link to comment Share on other sites More sharing options...
Not at the table Karlos Posted August 31, 2023 Share Posted August 31, 2023 23 minutes ago, GoBills808 said: I've never understood that rhetoric when it comes to medicinal cannabis. I mean, nobody thinks it's hugely important we make our own aspirin or whatever There's a big difference between watering a plant and manufacturing pills. 1 1 Quote Link to comment Share on other sites More sharing options...
GoBills808 Posted August 31, 2023 Share Posted August 31, 2023 Just now, Not at the table Karlos said: There's a big difference between watering a plant and manufacturing pills. Sure, if you're just looking to get high and not claiming to be manufacturing medicine Our local dispensaries here are subject to pretty rigorous quality standards Quote Link to comment Share on other sites More sharing options...
Bill from NYC Posted August 31, 2023 Share Posted August 31, 2023 28 minutes ago, GoBills808 said: I've never understood that rhetoric when it comes to medicinal cannabis. I mean, nobody thinks it's hugely important we make our own aspirin or whatever Pesticides? 4 minutes ago, Not at the table Karlos said: There's a big difference between watering a plant and manufacturing pills. Really, right? Quote Link to comment Share on other sites More sharing options...
GoBills808 Posted August 31, 2023 Share Posted August 31, 2023 2 minutes ago, Bill from NYC said: Pesticides? Really, right? What about pesticides? Quote Link to comment Share on other sites More sharing options...
Not at the table Karlos Posted August 31, 2023 Share Posted August 31, 2023 (edited) 7 minutes ago, GoBills808 said: Sure, if you're just looking to get high and not claiming to be manufacturing medicine Our local dispensaries here are subject to pretty rigorous quality standards Do you think there's a different process to growing weed to get high vs weed that's used medicinally? You may want more CBD so you grow a strain that has higher CBD. You're still watering and feeding it the same. The quality standards are checking for anything dangerous like chemicals or pesticides. I don't think you understand what you're talking about. Edited August 31, 2023 by Not at the table Karlos Quote Link to comment Share on other sites More sharing options...
GoBills808 Posted August 31, 2023 Share Posted August 31, 2023 1 minute ago, Not at the table Karlos said: Do you think there's a different process to growing weed to get high vs weed that's used medicinally? You may want more CBD so you grow a strain that has higher CBD. You're still watering and feeding it the same. The quality standards are checking for anything dangerous like chemicals or pesticides. There is absolutely a different process Not just 'chemicals and pesticides' that aren't meant to be combusted and inhaled or ingested, but mildew spores like bremia that can be harmful, foreign substances like mites or aphids Growing cannabis for medicine (at least in my state) and what you want to do is the difference between pickup basketball and the NBA, as it should be 1 Quote Link to comment Share on other sites More sharing options...
WhoTom Posted August 31, 2023 Share Posted August 31, 2023 38 minutes ago, GoBills808 said: I've never understood that rhetoric when it comes to medicinal cannabis. I mean, nobody thinks it's hugely important we make our own aspirin or whatever Aspirin is derived from the willow tree, but chewing on a willow twig won't give enough of the desired effect, so they extract the single active ingredient and mix it with others to produce aspirin. If THC, CBD, or some other cannabinoid works by itself, with no extraction or additional ingredients required, then cultivating one's own might make sense. Personally, I have a medical card and I use the dispensary, but the prices - even without the recreational tax - are outrageous. I eat the cost because I don't use much and I can afford it, but many others can't afford it. Now, if it's rescheduled to the point where doctors can prescribe it, then insurance will cover it and patients will only pay the co-pay, which may make home cultivation less attractive. Either way, rescheduling benefits medical users. Quote Link to comment Share on other sites More sharing options...
Bill from NYC Posted August 31, 2023 Share Posted August 31, 2023 6 minutes ago, GoBills808 said: What about pesticides? Well, farmers use them for tobacco. I am under the impression that they cause cancer. If they are used to grow tobacco, why should I believe that farmers won't use them to grow weed? I grow vegetables without them. If I was growing weed I would not spray the plants with pesticides. Now, do all weed farmers use them? I don't know. Do you? Btw, please don't take my post as being snide. I was a cigarette smoker until 8 years ago, so my body certainly took in enough poisonous substances. Quote Link to comment Share on other sites More sharing options...
Not at the table Karlos Posted August 31, 2023 Share Posted August 31, 2023 15 minutes ago, GoBills808 said: There is absolutely a different process Not just 'chemicals and pesticides' that aren't meant to be combusted and inhaled or ingested, but mildew spores like bremia that can be harmful, foreign substances like mites or aphids Growing cannabis for medicine (at least in my state) and what you want to do is the difference between pickup basketball and the NBA, as it should be Lmao. What I want to do? Or what I'm paid handsomely to do. Quote Link to comment Share on other sites More sharing options...
GoBills808 Posted August 31, 2023 Share Posted August 31, 2023 2 minutes ago, Bill from NYC said: Well, farmers use them for tobacco. I am under the impression that they cause cancer. If they are used to grow tobacco, why should I believe that farmers won't use them to grow weed? I grow vegetables without them. If I was growing weed I would not spray the plants with pesticides. Now, do all weed farmers use them? I don't know. Do you? Btw, please don't take my post as being snide. I was a cigarette smoker until 8 years ago, so my body certainly took in enough poisonous substances. I do farm but not a cannabis farmer There are some fairly well studied links between certain herbicides and cancers...they deal primarily w ingesting the substance. It's why one of the issues re: cannabis that's meant for smoking is tough because there isn't much literature on what happens when you burn these herbicides/pesticides and then inhale the smoke. Now you may not run into that issue but there are a lot of home gardeners who might. As far as I understand it, inhaling the product of combustion of anything isn't great for your health. That goes for tobacco, cannabis, campfires, whatever. full disclosure I used to smoke cigs also and was a heavy cannabis user in my youth 1 Quote Link to comment Share on other sites More sharing options...
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