While I agree with your concern... in past years I'd be downright freaking out - but those 2 and guys off the street - Don't forget Davis, but I guess Kumerow i guess falls into this category - is probably still a better combo than most teams have at their disposal. Depth is still a weapon the Bills can wield.
Personally I think the whole damn team needs to get the jab and be done with the shenanigans, but clearly that isn't going to happen.