I believe we are going to have a WR room that is going to be playing all over the field, interchangeable parts. I think you will see Samuel, Diggs, Shakir and Kincaid all operating a decent bit out of the slot and outside. I believe its going to be a very possession like passing with rushing attack mixed in with deep down the field passes.
Samuel has a lot of physical talents and he's somewhat versatile. He hasn't had good QB's throwing him the ball and the ones who have thrown it to him were his QB's for less than a year on average, so no chemistry was ever able to get established with the QB.
This gives the Bills some flexibility with who they can draft at the WR. They won't be pigeon holed to chase after a burner, they could be free to draft the best WR available and to me that sounds more appealing.