I think they are two evenly matched teams. A blow out either way seems highly unlikely in Buffalo. Agreed that Henry has been the X-factor in some games against his teams in recent years...except for the games where they shut him down pretty good. The only thing I can think of that increases the odds of a blow out either way is the increased variability week 1 brings with it being the first real game with changed rosters from last season on both sides.
A loss and getting 'rolled' are two different things. I can easily see a loss. Getting handily beaten at home would be a big surprise, at least to me.