If the G-Men fall behind, they are done. They have Barkley and Engram to catch passes this week. Thats about it. I'm gonna say Barkley goes 125+ total, just because he is great. But in the grand scheme, that will play into our hands as our DB's can hone in on him and Engram, with no real threat elsewhere. That being said, if we are nursing a steady lead throughout, I can see RB by committee for Buffalo. Really tough call, but I'd say Barkley has more yards. Bills get the win. 24-13