I love the Bills in this matchup. Couldn't be a better time to play the Colts. Too much mental strain from all the weaponary on offense for their D to handle on opening day, in front of a sellout crowd. Their best hope is to keep it close early, because it could be a blowout otherwise. The Bills pass rush with a comfortable lead will be a thing of beauty. And, with little or no track record of the Bills offense to plan for. They are in trouble.
JMO