FWIW, this is what @ScottLaw is referring to with Edmunds.
His hesitation here is a killer. The BACKSIDE GUARD was able to make the block here because he’s playing too much on his heels and not playing downhill quick enough. IMO he should have ran across and THROUGH THAT guard’s face. You see Milano scraping (he hesitates too and is late to the play) and had Edmunds gotten across the face of the Guard, I would imagine he’d be in position to close that gap down, possibly allowing Milano the time to get there.
McD’s one gap defense only works if everyone truly honors their gap. The hesitation comes from lack of trust. In this scenario, had both (or either) Edmunds and Milano been down hill and more decisive, I think this dead at the LOS.
this is just one example, but the 250 lb MLB has a tendency to play too often like a 150 lb player.