Exactly. All logic says that the Bills will lose, but this is not a computer program. It's a human game, with human emotions. Many would argue that this game is more important to the Bills. Which team would a loss hurt most? Desperation is a crazy thing.
These games are played on the field and not on paper for a reason. If you can look at an opponent and mark them down as a win or loss without fail, then why play the games? How many people can actually pick a team's won/lost record before the season and get every game right? You may get lucky and predict the correct record, but it's highly unlikely you'll get every game right. For all the nay sayers who want to put others down for believing the Bills have a chance, be careful...it's a long fall from atop that high horse on which you're perched.