Oline, specifically tackle is not a low value position. Neither is CB1. Yes, RB may be "low value" but he didnt just draft a good RB, he drafted one of the 5 best in the league. The Bills roster outside of WR has been solid for awhile now. Its aging out at some positions, severly injured at others. They need a bit of a reset. Which I think you'll see in the offseason.
On the point about not playing football, which he did in high school, its just a nonsense argument. Hes been in football, learning from scouts and general managers for close to 30 years. Not sure what sitting the bench in D3 college football would have taught him about the game that he doesnt already know.