Indy can avoid playing the Bills either way, assuming the Bills beat the Steelers. If the Rams win, Indy can avoid the Bills by beating the Broncos, sending the Bills to San Diego. If the Rams lose, Indy can keep the Bills out of the playoffs entirely by losing to Denver.
Of course, none of that probably enters their thinking anyway. I'm just worried that since Indy could face Denver two weeks in a row, they will play very vanilla this weekend in order to save everything for a possible playoff game against them.