It's a metric that Pro Football Reference made up, it stands for Approximate Value. Here's some information on it:
"AV is not meant to be a be-all end-all metric. Football stat lines just do not come close to capturing all the contributions of a player the way they do in baseball and basketball. If one player is a 16 and another is a 14, we can't be very confident that the 16AV player actually had a better season than the 14AV player. But I am pretty confident that the collection of all players with 16AV played better, as an entire group, than the collection of all players with 14AV."
"Essentially, AV is a substitute for --- and a significant improvement upon, in my opinion --- metrics like 'number of seasons as a starter' or 'number of times making the pro bowl' or the like. You should think of it as being essentially like those two metrics, but with interpolation in between. That is, 'number of seasons as a starter' is a reasonable starting point if you're trying to measure, say, how good a particular draft class is, or what kind of player you can expect to get with the #13 pick in the draft. But obviously some starters are better than others. Starters on good teams are, as a group, better than starters on bad teams. Starting WRs who had lots of receiving yards are, as a group, better than starting WRs who did not have many receiving yards. Starters who made the pro bowl are, as a group, better than starters who didn't, and so on. And non-starters aren't worthless, so they get some points too."
http://www.pro-football-reference.com/blog/index37a8.html