I see alot of responses with short passing being the answer. If The Bills can generate an effective pass rush with only 4 lineman rushing, then the short game can be neutralized with physical, in your face cornerback play and linebackers taking away the short passing lanes. As the Giants have showed, when a team can use only 4 lineman and can get to the quarterback or pressure him consistently, they are a very dificult defense to move the ball on. I think The Bills have this potential. Teams would have to keep the tightend in to help block and possibly a running back also.THis reduces the amount of weapons an offense can use. Really, any team that can consistently pressure the quarterback without sending extra rushers, is at a huge advantage over the offense.