There is a 99% chance they won't be able to trade down.
http://sports.espn.go.com/nfl/draft06/news/story?id=2410670
Our pick is worth 2200 points. If we "trade down" to say, the #10, we'd have to receive a 2nd, a 3rd, and a 4th to make up the points, and no team is going to do that. This draft crop isn't as great as years past. The #3 pick commands a lot more cash than a lower pick. Nobody knows if there will even be a season next year.
2004 was a big year for "trading down" (a great draft class, Eli wouldn't play in SD). After that, there wasn't any trading down done in the top 10 until 2009 when Dirty Sanchez was taken. Cleveland traded down, then traded down again. TB got Josh Freeman out of the deal. Cleveland got... Mohammad Massequoi, David Veikune (not on the team) and a CB (in the UFL).