I am Canadian and I am well aware of the differences in the game as I have watched it for 25 years, however I think the skill levels are night and day. The battles at the line of scrimmage would be no contest....with the wider field I could see the NFL teams sealing off the corners and taking the ball outside with ease. Can you imagine Mike O'Shea trying to catch Adrian Peterson or their corners trying to cover a big time receiver with all the open space. Yah it would take some adjustments for sure but I don't see it as being close at all. Just my 2 cents....(I am assuming the NFL teams get to use their own footballs as well)