Not trying to get ahead of myself but barring a complete collapse the Bills will be in a playoff game in a few weeks. If I am picking the easiest match up today I would go with
1A/B Mia / LAV.
2 Indy
3 Cle
4 Bal
5 Pit
6 Ten
7 KC
Lets look at the most likely scenarios:
#3 Seed is most likely scenario
#3 team plays #6 team so the Bills are likely playing:
Most likely is Indy or Tenn - whoever loses division
Other possibilities Mia, Cle, Bal
#2 Seed if Cle beats out Pit
#2 team plays #7 team so the Bills are likely playing:
Most likely is Mia or LAV whoever makes it between the two
Others could be any of Ind, Tenn, Bal
#4 Seed or #7 Seed if we stink and lose at least 2 of the last 3 games
#4 would likely mean playing either Pit or Cle, Bal has slight chance (loser of division)
#7 would most likely playing either Pit or Cle (winner of division), KC is small chance