My Aunt and Uncle came here in 2005 on a cruise like that. They flew to Fairbanks and took the Alaska railroad down to Anchorage with stops on the way [i remember them saying something about rafting]. Thats a cool trip from Fairbanks to ANC on the railroad, about 250 miles total and right though the Alaska range.
Day stop in Anchorage shown around by their beloved nephew, Then back on the train to Seward [also a cool ride] then on the ship for the cruise to Vancouver.