Kansas City (15-2) will host the Buffalo Bills (15-3) next Sunday with a return trip to the Super Bowl on the line for the Chiefs. Kansas City won the regular-season matchup 26-17 in Buffalo in Week 6.
''Great team. Big-time quarterback. Playmakers all over the place,'' Mathieu said of the Bills. ''A really, really good defense, so we're going to have our hands full next week.''
Mahomes' status won't be known until much later in the week. He threw a TD pass and ran for another score in the first half before getting hurt on a quarterback option midway through the third quarter.