In an episode of Punked, Ashton is wearing a Billls Bledsoe jersey.
In 90210 there is an episode where there is a transfer student from Buffalo and one of the guys say nothing good comes from Buffalo and they lost 3 Super Bowls in a row. The other guy corrects him and said it was 4 in a row.
In the movie Grudge Match Stallone says to De Niro that he had a gambling problem in the 90's and lost all his money betting on the Bills in the Super Bowl. De Niro said they went 4 times in a row, I thought they would win at least one!
In the move Two for the money, Pacino and McConaughey are at dinner and Pacino is talking about someone he doesnt like who asked him who he liked in the Buffalo/Miami game.
McConaughey laughed and said did you tell him Buffalo?
CBF