If you listened to CFNY on a Saturday Night, you were bound to hear "Homeboy" by Adorable.
The Chapel Hill area produced some great bands (e.g. Superchunk, Archers of Loaf)
Here's another oldie but goodie: http://youtube.com/watch?v=v0tOjAESwSY
Some other 90s bands: Buffalo Tom, Velocity Girl, Bettie Serveert, Yo La Tengo, Primal Scream, Stone Roses, Spinanes....