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Some interesting info I found, Will try in yellow as there might be spoilers for some people in here.
Trivia about Lost - The Complete First Season:
Jorge Garcia (I) missed his sister's wedding to shoot this show in Hawaii.
The first season depicts the first 40 days on the island.
The first episode debuted on ABC with 18.65 million viewers. The second episode attracted 16.33 million viewers.
Yoon-jin Kim originally read for the character of Kate. The producers felt she was not what they were looking for but decided to create a new character for her along with her character's spouse.
During Charlie's snorting scenes, Dominic Monaghan is actually snorting brown sugar.
Charlie's shoulder tattoo reads "Living is easy with eyes closed". This is a lyric from the song "Strawberry Fields" by The Beatles.
The rocks used in the waterfall cave set are made of rubber so that the sound of the actors, and crew members walking about are not picked up on camera.
When the idea was to have Jack killed off in the pilot, the creators discussed casting Michael Keaton as Jack.
The part of Charlie was originally written for someone much older, but when Dominic Monaghan auditioned, the writers and producers loved him so much that they set about re-writing the part to Dominic's strengths.
The book Sawyer reads is "Watership Down" by Richard Adams (IV). It tells the tale of a group of lost rabbits searching for a new home.
Plane wreckage scenes were filmed at Mokuleia Beach.
Jungle scenes depicting open, grassy pasture areas at the foot of jagged cliffs were filmed in Kaaawa Valley (first season).
Mokuleia Beach is near Oahu's northwest tip (Kaena Point). Kaaawa Valley is over 30 miles away on the island's eastern coast.
Kaaawa Valley is one of the few valleys on Oahu which are entirely privately owned. Many productions were filmed there, including Jurassic Park (1993)'s memorable hiding-behind-the-log chase scene.
Jorge Garcia (I) was the first actor to be cast as one of the survivors.
The sound stage where the cave scenes are filmed is at the old Xerox building.
John Locke is named after English philosopher John Locke, who theorized that before modern society, people lived in the wild in a state of equality and happiness. Likewise, Danielle Rousseau is named for Jean Jacques Rousseau, a French philosopher who wrote that society is corrupt, and that when removed from society, man can become truly noble.
Vincent, the dog, is actually played by a female dog, whose name is Madison.
In "Whatever the Case May Be" (Episode #1.12), Shannon describes having been in France and seeing a children's animated movie about "computer fish" that ends with the song "La Mer" (known as "Beyond the Sea" in English). Although Shannon doesn't know the name of the movie, it is clearly Finding Nemo (2003), although the French dub of Finding Nemo, like the original American movie, ended with Robbie Williams (I)'s English cover of "Beyond the Sea" instead of the French source. This show and Finding Nemo are both products of the same parent company, Disney.
The cast was not allowed to see a certain set. They had to cover their eyes until cameras rolled. They were walked down the path, cameras now on, and their reaction to seeing the cockpit leaning against the trees was real. This one-take is what was used in the pilot episode.
In the episode "The Homecoming" (2/9/05) Charlie's date Lucy mentions that her dad is out of town looking to buy a paper company in Slough. This is a reference to the British show "Office, The" (2001) which took place at a paper company in Slough.
The symbol that Claire wears around her neck is the Japanese kanji for "love".
Swedish TV channel TV4 were forced to cancel their broadcast of the series prematurely, because the remaining episodes were stolen.