One subtle disagreement - I live in the Bay Area and while Brock is a solid QB, most fans and media here would argue that the Niners are one Deebo or CMC injury away from being quite beatable on any given day by any decent team. Their offense is dependent on those two. Purdy is QB and gets the associated hype especially since he was a 7th rounder who is succeeding. But note that they were 0-3 without Deebo and Trent Williams, not without Purdy.
That said, when healthy, they are not a team I want the Bills to face. We are no better than a coin flip with our current injuries, but certainly have a chance with current level of play.