Chiefs finished 2nd in scoring and 4th against the pass but they are the 17th rated D against the run.
For comparison Bills D finished 4th in scoring and 7th against the pass and where a couple spots ahead of the Chiefs at 15th against the run.
This game more than likely will come down to Mahomes and Pacheco against Allen and Cook and who controls the clock. As both teams are very good at limiting explosive plays down field.