Agreed on the part about guests. Not necessarily interviews with players/management, you end up getting a bunch of cliches. But having reporters, analysts, even bloggers is pretty entertaining. They are more likely to say what they really feel.
Some of the best radio, is when Brad has Ruben Brown on. Former player who knows what he's talking about, and isn't afraid to give his real opinions.
If you do take calls, try to avoid calling every third caller a moron. (like a certain former co-worker).
I look forward to hearing some Bills talk on my lunch breaks for a change. (2nd shift)