Daboll is smart. I expect a different offense with Tyrod starting, heavily run oriented. And Tyrod will be his usual risk averse self, so barring fumbles (which may very well happen), no INTs making life easy for the Bills. I do think they’ll run the ball effectively - having a running QB gives the Giants’ offense a lot more opportunities on the ground.
The Bills should win, but if Tyrod stays healthy (a big if given how short his last starting opportunities lasted), I’m guessing the Giants keep the score respectable.