The point is, if these guys all go in the top 25 picks, they're probably better than you give them credit for.
But assuming they're not, why bother picking Nelson or Hubbard, either? If the guys above them in the draft order can't play, why should guys regarded as lesser prospects be able to?
IMO, if the Bills skip the position in R1, they probably shouldn't even bother drafting a WR until the 2nd day. I think all of those guys in the 2nd tier of WRs this year will struggle to ever beat out Parrish/Reed for the #2 spot. Given that, I'd rather just take a couple of receivers late and hope for the best. TE would be my R2 target if they go defense in R1.