Bob in Mich
-
Posts
1,749 -
Joined
-
Last visited
Content Type
Gallery
Profiles
Forums
Events
Posts posted by Bob in Mich
-
-
Wow, marijuana for medicine! Yeah right! What a joke. We all know that medical marijuana is just a big ruse organized by the stoners
I've never tried that stuff myself. I heard that it is bad for you. What about the long term effects? What about the children and the puppies, are you sure you are thinking clearly. Maybe that stuff already ruined your brain.
Was your experience like this? I heard they are like this.
lol Thanks for sharing your story. I hope you can experiment with some different strains and different delivery methods and find something that works well for your condition. You may still want to keep the vicodins for breakthrough pain but hopefully the cannabis can keep you away from daily opiate use. Good luck.
-
(This is a repost from the other marijuana thread in order to consolidate the information)
Here are listed some of the medicinal properties of THC for those that feel it is just for stoners. This info is from the link below.
THC is a partial agonist at CB1 and cannabinoid receptor 2 (CB2) analogous to AEA, and underlying many of its activities as a psychoactive agent, analgesic, muscle relaxant and antispasmodic. Additionally, it is a bronchodilator, neuroprotective antioxidant, antipruritic agent in cholestatic jaundice and has 20 times the anti-inflammatory power of aspirin and twice that of hydrocortisone. THC is likely to avoid potential pitfalls of either COX-1 or COX-2 inhibition, as such activity is only noted at concentrations far above those attained therapeutically.
This table shows the medicinal effects of the various cannabinoids and terpenes.
http://www.ncbi.nlm....946/table/tbl1/
Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects
-
A Glossary to Help in Deciphering the Research Studies
Thanks to poster 'in vivo' at the Michigan Medical Marijuana Association board, here is a glossary of terms with wiki links. The research reports that I linked to above use a lot of unfamiliar terms, at least to most of us. You might find this helpful.
http://michiganmedic...44364-glossary/
From the link
An agonist is a chemical that binds to some receptor of a cell and triggers a response by that cell. Agonists often mimic the action of a naturally occurring substance. Whereas an agonist causes an action, an antagonist blocks the action of the agonist and an inverse agonist causes an action opposite to that of the agonist.
-
Here are listed some of the medicinal properties of THC for those that feel it is just for stoners. This info is from the link below.
THC is a partial agonist at CB1 and cannabinoid receptor 2 (CB2) analogous to AEA, and underlying many of its activities as a psychoactive agent, analgesic, muscle relaxant and antispasmodic. Additionally, it is a bronchodilator, neuroprotective antioxidant, antipruritic agent in cholestatic jaundice and has 20 times the anti-inflammatory power of aspirin and twice that of hydrocortisone. THC is likely to avoid potential pitfalls of either COX-1 or COX-2 inhibition, as such activity is only noted at concentrations far above those attained therapeutically.
This table shows the medicinal effects of the various cannabinoids and terpenes.
http://www.ncbi.nlm....946/table/tbl1/
Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects
-
I was just watching the replay from last night's game and I wanted to mention one really bright spot.
Oh wait! Damn it! It is just a pixel problem on the TV screen.
Never mind, no bright spots.
-
I found this site of Beverly Hillbillies episodes. This is the one with Cookie
http://thebeverlyhillbillies.net/season-8-episode-24-simon-legree-drysdale/
-
CNN story on a young man that OD'd on pain killers. Apparently the Doctor misplaced his ethics
Adam's story: When prescription drugs are deadly
http://www.cnn.com/2014/08/26/health/diaz-prescription-drugs/index.html?hpt=hp_t4
From the article
In an affidavit, the DEA alleges that in the six weeks before Adam Montgomery's death, Dr. Diaz prescribed him a total of 2,087 pills, an average of 63 pills a day.
-
The dude needs some further instruction on making a suppository
-
Anyone hear if/when biopsy results will be known? How long does something like that take?
-
Does anyone think $36/month for NFL ST,NHL Center Ice,MLB,NBA,and NCAAF is a good deal?
CBF
It is a great deal. No doubt.
Is your wife good looking? If so you can buy one of those GPS tracking devices in case you're interested in where she goes at night.
-
After posting this information over the last few weeks and seeing the replies, in my opinion, cannabinoid deficiency MUST lead to the inability to absorb new information.
If you are coming late into this thread, please see the original post and please watch the video. It explains so much. https://www.youtube....h?v=XfO_MpDm5kc
For those with a short attention span, this video is under 4 and one half minutes. Doesn't have the visual aids but Dr Melamede does a great job explaining endocannabinoids.
Remember too that this information is meant to be a starting point. It does not mean that the solution to every problem mentioned here is to smoke a joint. In some cases the research reports mention blocking a cannabinoid receptor as the key. Some treatments call for a particular cannabinoid, some call for the whole plant. Choosing the wrong cannabis strain for treatment may make the health problem worse. Please do your own research.
Also, these postings are not some money making scheme. The only money that I have ever made on cannabis has been in the stock market. Since we are over 5 years into our medical cannabis period in Michigan, we have covered a lot of ground regarding cannabis and health. I was just hoping that what I could share here might help someone in the future. That's it, that is my entire scheme.
-
Clinical endocannabinoid deficiency (CECD) revisited: Can this concept explain the therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?
30-Jun-2014
http://www.ncbi.nlm....pubmed/24977967
From the Conclusion section of the report
Subsequent research has confirmed that underlying endocannabinoid deficiencies indeed play a role in migraine, fibromyalgia, irritable bowel syndrome and a growing list of other medical conditions. Clinical experience is bearing this out. Further research and especially, clinical trials will further demonstrate the usefulness of medical cannabis. As legal barriers fall and scientific bias fades this will become more apparent.
This is also an interesting article
Cannabinoid Deficiency May Explain A Variety Of Health Conditions
-
Before even more people get hurt they should outlaw those damn over the bed trapeze swings
-
I know ACL's are weird injuries, but when I was at camp I walked and chatted with Kiko for a brief second while he walked out to his car. He was in flip-flops, which I found odd considering the lack of support but he was walking fine, no limp.
Not that that matters much with an ACL, but I found it interesting.
You can do a whole lot without an ACL, certainly walking or running without a limp....after the initial injury has subsided. Very strong leg muscles surrounding the knee along with very good reaction time lets a person get by ALMOST all of the time without an ACL.
The problem is that when athletics are involved, the forces on the knee can be great. If the blow or twist to the knee is unexpected or if the force is too great, the knee will buckle. When it buckles under great force, it usually takes other structures along with it like other ligaments, bone, tendon, etc. and you have compounded the problems
-
Hey Performer, any chance someone special in your life could possibly take away your computer privileges? Sammy maybe?? Oh please say yes, oh please!!!
-
For many pain/seizure issues it's strains with virtually no THC. So that leads me to one conclusion. People looking for medical marijuana high in THC = stoners. So I would love to see the amount of marijuana sales from these dispensaries where people are asking for strains high in THC.
That is a bad conclusion, Chef. CBD has gotten the coverage lately from Sanjay Gupta and that is great but it is certain that the other cannabinoids have medicinal properties too, including THC.
Recall too that most studies now talk about the 'entourage effect' of the cannabinoids working more effectively in concert.
It would be a big mistake to assume that we should just extract the CBD and throw out the rest of the plant.
-
Chronic Pain And The Therapeutic Benefits Of Medical Cannabis
http://www.medicaljane.com/2014/06/13/chronic-pain-and-the-theraputic-benefits-of-medical-cannabis/
From the article
The fact that these receptors are found in the two major body systems responsible for producing the sensation of pain, the immune system and the nervous system is what gives cannabis its therapeutic relevance in the chronic pain space.
Additionally, and importantly, there are a lack of cannabinoid receptors in the brainstem region, the area of the brain responsible for controlling breathing, thus the dangerous side effect of respiratory depression found with high dose opioid use, is not a factor in cannabis therapy.
In practical application, cannabis therapy can be used in conjunction with other chronic pain therapies. In his clinical practice, Dr. Rabe reports, “We have many patients who come in on higher doses of opioid medications. Through using cannabis, in conjunction with other therapies, they are able to lower their daily opioid requirement.”
This is a fairly recent overview/study of the subject
-
Medical marijuana laws may reduce painkiller overdoses
By Saundra Young, CNN
updated 4:23 PM EDT, Mon August 25, 2014
http://www.cnn.com/2....html?hpt=hp_t2
From the article
States that have legalized marijuana for managing chronic pain have significantly fewer deaths from prescription painkiller overdoses each year, according to a new study published Monday in JAMA Internal Medicine...
.
"We found there was about a 25% lower rate of prescription painkiller overdose deaths on average after implementation of a medical marijuana law," lead study author Dr. Marcus Bachhuber said.
-
This is my understanding of how it can be effective on so many illnesses.
(Recall that I am not a medical professional )
The reason it works on so many diseases is that cannabinoids are similar to our body's own endocannabinoid molecules which are used to regulate very many bodily processes. The endocannabinoids are used to communicate between many different cell types in our bodies. Cannabinoid receptors are found in nearly every organ in the body
When we are healthy, we can self regulate imbalances that happen in our bodies. We are designed to do just that. Endocannabinoids, as it turns out, are one of the messenger molecules used by our body to self regulate. This includes things like blood pressure, blood sugar, inflammation response, nerve signals, and more. Cannabinoids often provide a feedback signal in the messaging process
Consider that if the body is lacking in messenger molecules, the natural re-balancing signals do not get through and so the body does not bring itself back into balance.
We can, in some cases, provide plant molecules that so closely resemble our own endocannabinoids that these are able to function as the messengers. Once the signals are restored, the body again self regulates and brings itself back into balance.
-
Please just give us the punchline already or stop with this lame pregnant cousin Brenda tale. This is your 4th try at getting someone to bite.
-
For some conditions, a high CBD strain is just the ticket.
For some other conditions though, the THC is apparently the key to the effectiveness of the cannabis. In my opinion, many of the cannabinoids offer hope of medicinal properties. There just needs to be more research.
http://www.cureyouro...cers-cells.html
Study Finds Cannabinoids Can Kill Gastric Cancer Cells
from the article
This study published in both journals offers hope in treating gastric cancers with cannabis. The researchers in Korea have discovered that WIN 55,212-2, a synthetic version of the cannabinoid THC that is found in cannabis, is antineoplastic. That means it can inhibit and prevent the growth and development of malignant gastric cancer cells.
-
No doubt. But, there are a ton of these that run counter to the "all pot does is mellow you out."..............Remember the guy in Florida who they thought was on bath salts when he ate the other guys face on the street. No, turned out it was just pot. (IIRC)
It was not widely reported but that guy was blind and the face eating took place just 14 feet from the entrance to a Honey Baked Ham store. I think it was all a case of mistaken identity.
-
bbb, cannabis contains about 100 cannabinoids in varying proportions depending on the strain.
One of them, THC, can make things worse for the psychotic person. One cannabinoid, CBD, can help calm that same person.
Depending on the ratio of these compounds found in an individual strain, a high THC strain could trigger an anxiety attack where another strain, one high in CBD, could bring someone down from an anxiety attack.
-
Turns out those Libyan attacks were carried out by a small town from North Dakota. They were just testing their new policing equipment.
Know anyone with a disease? Read this
in Politics, Polls, and Pundits
Posted
Old dope, new tricks: the new science of medical cannabis
26 August 2014, 9.48pm BST
http://theconversati...-cannabis-30828
This is from an Australian article
THC clearly has important therapeutic effects in multiple sclerosis and pain, in stimulating appetite in HIV or cancer patients, and even for anxiety disorders, such as post-traumatic stress disorder.
No medicine is perfect: opiates control pain but may be addictive and constipating; antidepressants lift mood but may numb you out and ruin your sex life; statins can lower your cholesterol but can cause muscle wastage. All drugs are poisons, it’s just a matter of the dose you’re taking.
Cannabis has its own positives and negatives, and the risks involved in its regular use, particularly during adolescence, continue to be well ventilated. But if we’re clever about our use, then it can be a most valuable therapeutic: a voyage of rediscovery is long overdue.