I think the Colts will show that they aren't the best team in the league after their bye week, when they play WSH, @DEN, @NE, BUF, @Dallas, Philadelphia, @Tennessee, @Jacksonville, Cincy. Pretty tough stretch there.
The name to the game of beating Indy is to stop their passing game on defense, and move the ball against them on offense.
You can run on the Colts. Houston put up over 100 yards with a craptastic offensive line, The Giants put up 186, Jacksonville put up 191, and the Jets put up 135.
They'll be in every game because of their offense, but they'll be beat by a team which plays ball control offense, strong defense, and limits turnovers.
Denver, New England, Buffalo, Dallas, Jacksonville, and Cincinnati can all do this. If Jacksonville plays better special teams, they win that first game vs Indy.
The Colts are good, but I still don't think they are good enough to win a superbowl.