The stolen timeout on the injury was most costly, and simply unprecedented in all the games I've watched which is a whole lot of games. Never seen that. It's a really shady ruling taken together with a lot of other shady calls makes this look like a very very shady game.
If the Bills had that timeout they would have kicked it away deep to save clock, probably get the ball back near their 25 with > 1:00. It was critical, in hindsight, but a butterfly effect of all the shading going on from this ***** crew.