Buffalo Bills Fan

Arizona 3 days ago fox news posted on it. Busy day I'll link it later still on phone saw it couple minutes ago

Don't forget about as well CDC covid19 Kawasaki like happening to kids as well. I think school's going to use caution. On the phone hard to link and details. I think know what I mean?

Agree first part. Want a safe and effective vaccine. Understandable some people question it. Have questions as well. Until proves help people out.

Studies Report Rapid Loss of COVID-19 Antibodies The results, while preliminary, suggest that survivors of SARS-CoV-2 infection may be susceptible to reinfection within weeks or months. Amanda Heidt Jun 19, 2020 14.5K ABOVE: © ISTOCK.COM, CHRISTOPH BURGSTEDT Apair of studies published this week is shedding light on the duration of immunity following COVID-19, showing patients lose their IgG antibodies—the virus-specific, slower-forming antibodies associated with long-term immunity—within weeks or months after recovery. With COVID-19, most people who become infected do produce antibodies, and even small amounts can still neutralize the virus in vitro, according to earlier work. These latest studies could not determine if a lack of antibodies leaves people at risk of reinfection. One of the studies found that 10 percent of nearly 1,500 COVID-positive patients registered undetectable antibody levels within weeks of first showing symptoms, while the other of 74 patients found they typically lost their antibodies two to three months after recovering from the infection, especially among those who tested positive but were asymptomatic. In contrast, infections caused by coronavirus cousins such as SARS and MERS result in antibodies that remain in the body for nearly a year, according to The New York Times. The first study, published June 16 on the preprint server medRxiv, screened for antibodies in almost 1,500 coronavirus patients in Wuhan, China. The researchers compared their levels to three other groups: nearly 20,000 members of the general population; more than 1,600 patients hospitalized for reasons other than COVID-19; and more than 3,800 medical workers, whom the authors assumed had “inevitably” been exposed to the virus in its early days, meaning they should have developed antibodies. They found that while almost 90 percent of COVID-19 patients had antibodies, roughly 1 percent to 5 percent of individuals in the others groups had them as well. The authors conclude in their paper that the remaining 10 percent of infected patients with no detectable antibodies, combined with the lack of antibodies in healthcare workers, suggest that “after SARS-CoV-2 infection, people are unlikely to produce long-lasting protective antibodies against this virus.” https://www.the-scientist.com/news-opinion/studies-report-rapid-loss-of-covid-19-antibodies-67650 Cousin to this covid19 report says only a year of antibodies only last. Not for sure but really need more studies how long antibodies last. Why I don't comment antibodies until real research. Some say this covid19 only two months antibodies( who knows) Emerg Infect Dis. 2007 Oct; 13(10): 1562–1564. doi: 10.3201/eid1310.070576 PMCID: PMC2851497 PMID: 18258008 Duration of Antibody Responses after Severe Acute Respiratory Syndrome Li-Ping Wu,* Nai-Chang Wang,* Yi-Hua Chang,* Xiang-Yi Tian,* Dan-Yu Na,* Li-Yuan Zhang,* Lei Zheng,* Tao Lan,† Lin-Fa Wang,‡ and Guo-***** Liang§ Author information Copyright and License information Disclaimer This article has been cited by other articles in PMC. Go to: Abstract Among 176 patients who had had severe acute respiratory syndrome (SARS), SARS-specific antibodies were maintained for an average of 2 years, and significant reduction of immunoglobulin G–positive percentage and titers occurred in the third year. Thus, SARS patients might be susceptible to reinfection >3 years after initial exposure. Keywords: SARS, convalescent, antibodies, longitudinal study, dispatch Severe acute respiratory syndrome (SARS) represents the first pandemic transmissible disease to emerge in this century. It was caused by a previously unknown coronavirus, the SARS-associated coronavirus (SARS-CoV) (1). SARS-CoV spreads from animals to humans by a rapid adaptation and evolution process (2,3). A large number of closely related viruses are present in wildlife reservoir populations (4–6). Therefore, due to cross-species transmission of the same or a similar coronavirus, SARS could recur. Immune protection against infection with other human coronaviruses, such as OC43 and 229E, is short-lived (7). To assess SARS patients’ risk for future reinfection, we conducted a longitudinal study of immunity in convalescent patients. Go to: The Study Shanxi Province in China was 1 of the SARS epicenters during the 2002–03 outbreaks. For our study, serum samples were taken from patients in 7 designated SARS hospitals in the province during March–August 2003. Follow-up serum samples were taken at 6 months, 1, 2, and 3 years after the onset of symptoms. A total of 176 cases that met the World Health Organization (WHO) SARS case definition (8) and had known transmission history were included in this study. The study was conducted as part of a national SARS control and prevention program; use of serum from human participants was approved by the Committee for SARS Control and Prevention, Department of Science and Technology, the People’s Republic of China. Titers of serum antibodies to SARS-CoV were determined by using a commercially available ELISA kit (BJI-GBI Biotechnology, Beijing, China). The ELISA was based on an inactivated preparation of whole-virus lysate. The kit was the first commercial kit approved by the Chinese Food and Drug Administration for specific detection of SARS-CoV antibodies and has been widely used in several studies (9–11). Manufacturer’s instructions were followed without modification. Briefly, for every ELISA plate, 1 blank, 1 positive, and 2 negative controls were included. For detection of immunoglobulin G (IgG), a 1:10 dilution of testing serum (100 μL) was added to antigen-coated wells, and the plate was incubated at 37oC for 30 min. Horseradish peroxide (HRP)–conjugated antihuman IgG (100 μL) was then added for detection of bound antibodies. For detection of IgM, the incubation of primary antibodies was extended to 60 min, followed by detection with HRP-conjugated antihuman IgM. Optical density (OD) readings were deemed valid only when the negative control OD was <0.10 and the positive control was >0.50 on the same ELISA plate. The cutoff for IgG and IgM determination was defined as 0.13 and 0.11, respectively, plus OD of the negative control. When the OD of the negative control was <0.05, 0.05 was used for the calculation. In this study, the OD readings of negative controls from different testing were consistently <0.05, so the cutoff ODs for IgG and IgM were 0.18 and 0.16, respectively. Serum samples that had an OD greater than or equal to the cutoff value were considered positive. Weak positive samples (i.e., OD<2× cutoff value) were retested in duplicate on the same day; only reproducible positive results were included in the final analysis. All data were processed by using Excel version 7.0 (Microsoft Corp., Redmond, WA, USA) and SPSS software version 10 for Windows (SPSS Inc., Chicago, IL, USA). Among the cohort, 163 (92.61%) of 176 (χ2 = 200.11, p = 0.000002) were IgG positive, which indicated that most patients who met the WHO case definition were indeed infected with SARS-CoV. As shown in the Table, at ≈7 days after the onset of symptoms, the percentage who were IgG positive was ≈11.80%. This percentage continued to increase, reached 100% at 90 days, and remained largely unchanged up to 200 days. Furthermore, after 1 and 2 years 93.88% and 89.58% of patients, respectively, were IgG positive, which suggests that the immune responses were maintained in >90% of patients for 2 years. However, 3 years later, ≈50% of the convalescent population had no SARS-CoV–specific IgG. The OD changes correlated with the changes to the IgG-positive percentage, although the rate of change varied. Both the OD readings (0.93) and positive percentages peaked at 90–120 days; however, the rate of reduction of the average OD readings was much faster, dropping by 22% (0.73) and 40% (0.54) at 1 and 2 years, respectively, after symptom onset (Figure 1). Figure 1 Change of immunoglobulin G (IgG) patterns among 176 convalescent severe acute respiratory syndrome patients with known transmission history. See the Table for number of samples used for the calculation at each time point. OD, optical density. A similar observation was obtained for IgM trends in this same cohort. The percentage of patients who were IgM positive within the first 7 days was 21.4% and peaked at 76.2% after 21–30 days (Table). The patterns of IgM-positive percentage and average OD readings were similar; both peaked at 21–30 days. After 60 days, the average OD readings dropped to 0.167, close to the cutoff value of 0.160. Table Cumulative rates of SARS-CoV antibodies among 176 SARS patients with known transmission histories* Time after symptom onset, d IgG IgM† No. samples tested No. positive samples (%) Average OD No. samples tested No. positive samples (%) Average OD 0–7 17 2 (11.76) 0.046 14 3 (21.43) 0.136 8–14 26 10 (38.46) 0.190 22 14 (63.64) 0.312 15–20 22 17 (77.27) 0.351 19 12 (63.16) 0.477 21–30 36 33 (91.67) 0.493 21 16 (76.19) 0.560 31–60 72 67 (93.06) 0.627 22 14 (63.64) 0.320 61–90 35 33 (94.29) 0.745 15 5 (33.33) 0.167 91–120 11 11 (100.00) 0.965 ND ND ND 121–210 23 23 (100.00) 0.932 ND ND ND 211–365 49 46 (93.88) 0.734 ND ND ND 366–763 96 86 (89.58) 0.535 ND ND ND 764–1,265 28 15 (53.57) 0.250 ND ND ND *SARS-CoV, severe acute respiratory syndrome–associated coronavirus; Ig, immunoglobulin; OD, optical density; ND, not determined because for most samples the IgM readings already reached background level on day 90. †For some patients, we did not have enough serum to test for IgM after testing for IgG; hence, a smaller number of serum samples were tested for IgM than for IgG. Among the cohort of patients with known transmission histories, we were able to obtain a complete collection of serum samples from 18 patients at 6 months, 1, 2, and 3 years. The IgG levels of these 18 patients were analyzed separately to obtain an IgG trend that more accurately represented convalescent SARS patients (Figure 2). All 18 patients had positive IgG at 6 months and at 1 year (i.e., 100% positive); only 1 patient became IgG negative at 2 years. However, at 3 years, the positive percentage dropped to 55.56%. The reduction of OD values mimicked that of the positive percentage, again at a faster rate. The average OD readings dropped from 0.94 at 6 months to 0.64 at 1 year, which represents a reduction of 33.33%. The OD further dropped to 0.52 (45.83% reduction) by 2 years and to 0.25 by 3 years. Figure 2 Change of immunoglobulin G (IgG) patterns among 18 convalescent severe acute respiratory syndrome patients with a complete collection of sequential serum samples at the time points shown. The 18 patients were selected from the cohort of 176 patients for whom transmission history was known. OD, optical density. Go to: Conclusions To our knowledge, the 3-year follow-up conducted in this study is the longest longitudinal study ever reported. With a large number of patients who had confirmed transmission history (176) and a complete dataset for 18, the level of confidence is high that the results obtained in this study are representative for convalescent SARS patients. Similar results have been reported from longitudinal studies of SARS patients with smaller cohort size (18–98 patients) and shorter follow-up period (240 days to 2 years) (9–14). The general trend of IgM peaking at ≈1 month after symptom onset and IgG peaking at 2–4 months was consistent among different studies. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851497/ Cousin to covid19 antibodies in the past. Real research on

Right seems scripted. Getting tired of all the madness world is bringing.

Wow on data on this.

np. In the end we all are humans. People have to support each other. Biggest downside to politics. Causes friction. You could be a amazing person. But in person don't talk much in politics. Understand people are different on it. Don't want to ruin friendship. My mother thinks biden is amazing but don't say much to her on it she's amazing respect her views. But in the end we all are humans in this together. If I was at George Floyd I'd do anything to stop the police from the person suffering. For this forward here going to respect others views try to respect them more. Let's go Buffalo bills this year as we all Bills fans lol.

Truly understand. Just looking at you're both sakes. Cooling it down to help you both out.

Jesus Fox can post here. Why PM Foxx? Sounds like you're getting aggressive. Settle damn down. If you can't handle a civil discussion then leave.

Sorry it is not a excuse.

Business and people need to work. Money man just to live. Business needs money survive among many other things. Rather try and not do anything in that.

So many amazing things destroyed . Don't make sense anymore anyone supporting Democrats. There just epic crazy. Wow people doing for sake tearing things down. None of it making any sense now.

Well there kids have to have something for future. Gotta understand everyone situtions different. Would be same boat if I had kids. I'm sorry. Love people here. There is sitution's many people including you don't need to know. People here are nice. Love other post and seeing people here. Before judge me went thru many crap some might be worst you can think but people are awesome. Usly go away in life to see people here makes things easier. I have major PTSD over lots of things but people awesome make me forget it.

Protesting is the cure for covid19 what democrats think lol.

Agreed man. Appreciate you here helping us with info evidence or whatever man. Don't let him get to you. Thanks for solid stuff helping out buddy.

Magic thanks for your posts very informative. Might disagree small things here and there. But in large agree and been very helpful with your info.

CORONAVIRUS Published 1 day ago Texas woman tests positive for coronavirus for second time By Kayla Rivas | Fox News Facebook Twitter Flipboard Comments Print Email close Fox News Flash top headlines for June 17 A woman in Texas recently took to social media, sharing her tearful journey after she says she contracted COVID-19 twice. Meredith McKee urged her Facebook followers to take the disease seriously, and uploaded pictures from her hospital bed at Texas Health Presbyterian in Dallas, swathed in a face mask and gown. TO PROTECT AGAINST CORONAVIRUS, CDC SAYS TO HAVE THESE 3 ITEMS ON HAND WHEN VENTURING OUT “For the SECOND time in 12 weeks I have contracted Covid19. Yes, you can get it again & it hit me like a ton of bricks...again,” McKee wrote. She said the infection was different the second time around “but no less horrendous.” McKee wrote that she sought hospital care due to high blood pressure. “I knew there was a serious problem,” she wrote. SCIENTIST DEMONSTRATES IMPORTANCE OF CORONAVIRUS FACE MASK USE IN UNIQUE AIRFLOW VIDEO The woman told NBC-5 when she was diagnosed in February, she had “clear and obvious” symptoms, like a dry cough. She reportedly fought the virus at home and beat the disease. An antibody test allegedly detected a positive presence of antibodies, and McKee claims she donated her plasma in an effort to help others overcome the virus. https://www.foxnews.com/health/texas-woman-tests-coronavirus-positive-for-second-time

You've chosen to ignore content by BillStime. Options We all should do the same ignore BillStime.! Niagara Bill is blaming deaths on Pence now. I think he's trying to say. Trying to say loves bible but ignores people died from covid19. As well as trying to say ignore mask and growing numbers. I'd say to him fake news!

Right. Know each person here is different. That person just talking crap

You're nuts no evidence accusing everyone here. Zero evidence. Why you're taking bs. BTW I'm one person and name. Ask the mods If want to get total proof. Don't accuse me without any evidence.

Jesus that man should be jail arrested 100 times. ***** thing to do to a old lady. Hope she is ok. And this guy face the law and jail.

Hopefully not anytime soon or not by covid19 (covid go to hell) But someday we all will be when we are old and discussing on here when we all are 80S in age LOL

I think the virus was pretty complexed people didn't know what to do of yet. I wish other countries have knowledge back then. as of right now Might of saved tons of people. The human body is unique. The meds, blood thinner for clots, preventing strokes among other things with the virus. If I get it noticed rash or something i'm going to hospital fast. (with virus) Plus I think people know about vitamins helps out lots. Know some friends drink all the time day and night. Just worry about them getting the virus the liver among other things a problem. Oxidative stress, endothelial dysfunction. With this virus have to be healthy with it. Like high fructose corn syrup just bad for you all ways. People can make food healthier for people. Frutose reduce vitamin d. As well as obesity and blood sugar problems,. Alcohol causes Oxiative stress as well. But anyway's the knowledge today people have helps lots. Better attacking this virus. Help solve people out.

CORONAVIRUS Published 1 day ago 'Life-saving' coronavirus drug discovered by Oxford researchers By Chris Ciaccia | Fox News Facebook Twitter Flipboard Comments Print Email close Fox News Flash top headlines for June 16 Researchers at Oxford University have discovered what is believed to be the first evidence of a drug that can reduce the risk of death from COVID-19 by up to one-third, a steroid known as dexamethasone. The drug, which is "instantly available and affordable worldwide" and is also a steroid, was found to reduce deaths in patients receiving oxygen by one-fifth and those on ventilators by one-third, according to preliminary results released Tuesday. "Dexamethasone is the first drug to be shown to improve survival in COVID-19. This is an extremely welcome result," Peter Horby, Professor of Emerging Infectious Diseases in the Nuffield Department of Medicine, University of Oxford, and one of the Chief Investigators for the trial, said in a statement. "The survival benefit is clear and large in those patients who are sick enough to require oxygen treatment, so dexamethasone should now become standard of care in these patients. Dexamethasone is inexpensive, on the shelf, and can be used immediately to save lives worldwide." COVID-19 IS 12 TIMES DEADLIER FOR PATIENTS WITH UNDERLYING HEALTH CONDITIONS: CDC Scott Gottlieb, the former head of the Food and Drug Administration, called the results a "robust finding," adding it could have "meaningful" implications. Scott Gottlieb, MD✔@ScottGottliebMD This is a robust finding and could meaningful affect outcomes. We're learning how to better treat advanced Covid disease and, combined with other new strategies like anticoagulation, we should see Covid mortality rates decline as long as we preserve our healthcare capacity. https://twitter.com/SquawkCNBC/status/1272872980104777728 … Squawk Box✔@SquawkCNBC "This is a very positive finding and it's a robust finding. It's a well-done study ... it certainly suggests that this could be beneficial in this setting. This is an important finding here today." @ScottGottliebMD gives initial thoughts on #dexamethasone as a #COVID19 treatment. 686 9:44 AM - Jun 16, 2020 Twitter Ads info and privacy 247 people are talking about this The results of the study will be released soon, the researchers said. The funding for the study was provided by the U.K. government, as well as private donors, including the Bill and Melinda Gates Foundation. The study, known as the RECOVERY Trial, enrolled more than 11,000 patients in England, Scotland, Wales and Northern Ireland. Some 2,104 patients were randomly assigned to get the drug, while another 4,321 patients received usual care, the Associated Press reported. Other patients received the HIV combo drug lopinavir-ritonavir, the antibiotic azithromycin; the anti-inflammatory drug tocilizumab, or plasma from recovered COVID-19 patients. https://www.foxnews.com/science/life-saving-coronavirus-drug-discovered-by-oxford-researchers