TO may be on the downside, but he's still a top-flight WR. His 10 TD's last year attest to that fact. I don't care why he's in Buffalo, just that he's in Buffalo. Rhodes as I said will be a backup and short-yardage guy. The Bills won't depend on him to carry the load, barring injury. Both will defintely help the Bills.
As for the playbook, I think it's safe to say that it will be opened-up. When you have the collection of talent the Bills do at the skill positions, especially a guy like TO who will rip you apart publicly if you play not to win, I have no worries that they'll play like they did the past few years, when they were hamstrung by having no #2 WR and poor/inexperienced QB play.
Peters' Goodfellas-inspired "F you, pay me" after one Pro Bowl appearance, after the Bills took a chance on him after the 2005 season and gave him a nice raise, was the height of egotism. The Bills made the best of a bad situation and made him someone else's headache. And the Bills have options on the O-line. What Trent lacks in a well-established O-line, gets made up by the receivers and RB's he has around him.