‘Two of Buffalo’s offensive coaches will play against their former team in the Saints on Sunday. Bills offensive coordinator Joe Brady coached for New Orleans from 2017-18 as an offensive assistant and quarterbacks coach Ronald Curry spent 2016-23 with the Saints in various roles.’
BillsBeat - September 28, 2025
Buffalo Bills vs. New Orleans Saints Game Predictions | Week 4
‘This is back-to-back road trips across the country for the Saints, while the Bills will be rested for 10 days having played on a Thursday. That’s a brutal combination. But the Bills are also the best team in the league. This is going to be ugly. Josh Allen lights up the Saints.’
Buffalo Bills vs. New Orleans Saints | Where to watch, stream and listen | Week 4
‘TV Channel: CBS. Local: WIVB. Time: 1 p.m.’
What Bills fans can expect at Highmark Stadium for Bills vs. Saints
‘Enjoy a special halftime performance from the University at Buffalo Marching Band! Known as the Thunder of the East, this 180 member powerhouse storms the field with energy, spirit, and pride — representing UB and all of Western New York. Let’s go Buffalo!’
BillsBeat - September 27, 2025
David Edwards' journey from option QB to key cog on the Bills' offensive line
‘His teammates, no matter which position they play, mean everything to Edwards. They’ve been through a lot during his time here. They’re why he’s meticulous in meetings and a perfectionist on the field. Edwards learned through his circuitous journey in football to cherish those impenetrable bonds built during practices in the sweltering summer heat and games on the snow-covered field at Highmark Stadium.’
Bills notes: Right tackle Spencer Brown, defensive end A.J. Epenesa questionable
‘Ahead of practice, McDermott said that right tackle Spencer Brown (calf) and defensive end A.J. Epenesa (pectoral) would be limited in Friday’s practice and will be questionable for Sunday’s game. Both were participating during the portion open to media, which on Fridays consists of just stretching.’
Erik Brady: He's a Bills season ticket holder again for the first time since boyhood
‘”It feels like my connection to Buffalo is as strong and alive as it has ever been,” he said, “even though I haven’t had an address in Buffalo since high school.”‘
Bills locked up 5 young players but one has yet to live up to his new contract
‘However, three games into 2025, Rousseau is the only one who hasn’t quite lived up to his new deal. The 24-year-old edge rusher was guaranteed $38.8 million at signing and that currently ranks as the eighth-most at his position in the NFL, but his performance has lagged behind many of those players both ahead and behind him on the pay scale.’
McDermott makes it official, says Bills will be without two key defenders vs Saints
‘Friday morning coach Sean McDermott ruled out both tackle Ed Oliver (ankle) and linebacker Matt Milano (pectoral muscle) for Sunday’s game against the New Orleans Saints at Highmark Stadium.’
Buffalo Bills’ A.J. Epenesa details pec injury as game status vs. Saints remains uncertain
‘“It hurts a good amount if you use it,” Epenesa said on Friday after practice. “and it’s a very specific movement that activates it or flares it up. It’s more of a pain tolerance thing.”’
Bills enter Sunday as massive favorites over Saints
‘Oliver’s absence likely means more playing time for rookie DTs Deone Walker and TJ Sanders. Walker flashed against Miami with the pressure that forced the eventual winning interception by Terrel Bernard, and he has looked further along through three games. Sanders has struggled at times in his rookie year, but he should have another opportunity this week to make some corrections.’
Bills looking to prevent Saints' no-huddle attack from providing struggling offense a spark
‘Remember the last time the New Orleans Saints came marching into Highmark Stadium? Anyone associated with the Buffalo Bills that would probably like to forget it. The Saints ran for 144 of their 298 yards in the second half to bury the Bills 47-10.’
Saturday's New Orleans Coverage
Why the Saints are encouraged they’ll cut down on heavy number of penalties (New Orleans Times Picayune)
Rod Walker: A step up in weight class means the Saints will face the ‘Million-Dollar Arm’ (New Orleans Times Picayune)
The Saints rule out two players ahead of Sunday’s game against the Buffalo Bills (New Orleans Times Picayune)
Saints defensive end Chase Young remains out with calf injury (ESPN)
Saints final Week 4 injury report: Starting OL healthy for first time in 2025 season (WWL-AM)
Saints Friday Injury Report: 2025 Week 4 vs. Buffalo Bills (NewOrleansSaints.com)
Bills defense takes hit as DT Oliver, LB Milano ruled out
‘Right tackle Spencer Brown (calf) and defensive end AJ Epenesa (pectoral) will be questionable vs. the Saints (1 p.m. ET, CBS). Oliver, Milano and Brown did not practice on Wednesday and Thursday, but Brown is set to be limited in Friday’s practice, per McDermott. Epenesa has been a limited participant throughout the week.’
Bills RB James Cook is proving he's worth the money
‘The Buffalo Bills running back has already made an offensive impact in the team’s first three games, picking up where he left off last season. Cook is second in the league in rushing yards (284), tied for the most rushing touchdowns with Philadelphia Eagles quarterback Jalen Hurts (four) and, in part thanks to another strong start by the Bills’ offensive line, leads the league in rushing yards before first contact (145).’