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‘The pick: Under 45.5. If the Saints are going to be without this many key players, it’s hard to imagine that Trevor Siemian will be able to put many points on the board, especially against this Buffalo defense that is still No. 1 in the NFL in DVOA entering Week 12. Even with the Bills averaging 31 points per game on the road this season, it’s hard banking on the Saints to carry out their end of the bargain to have this go over.’

‘This wasn’t the sharpest game by Josh Allen, who completed 21 of 35 for 209 yards, two touchdowns and two picks. Part of that was due to the rainy weather in Buffalo, but he also had a couple of poor decisions in the loss. Meanwhile, Carson Wentz completed 11 of 20 for 106 yards and a touchdown. On top of those five touchdowns, Taylor finished his day with 185 yards rushing and caught all three of his targets for 19 yards. He also became the first running back in the NFL to surpass 1,000 yards rushing this season in the midst of this win.’

‘If you’re not familiar with Scorigami, it’s pretty simple: The internet cheers when the NFL gives us a final score that’s never been seen before and that’s what the Colts’ 41-15 upset win over the Bills gave us on Sunday.’

‘Buffalo does struggle with their run defense to the right of the field, allowing 4.7 yards per carry (10th-most in the league). This matchup will be the one to watch Sunday.’

‘The Bills’ offense is going to score points, so Sunday’s game will likely come down to how many points the Jets’ offense can score against Buffalo’s formidable defense. White and the Jets’ offense are capable of putting together at least a few scoring drives against the Bills, but probably not enough to keep pace with Allen and the Bills’ offense. Expect a big game from Allen and receiver Stefon Diggs, who caught 20 passes during the Bills’ last three games.’

‘Incredibly, as you can see above, the Bills have been involved in four of the seven largest upsets in the last 30-plus years, including two of them in the last four seasons.’

‘Don’t be surprised if this game is closer than expected, at least for the first two or three quarters. The Jaguars’ defense has made strides, while their offense is starting to find an identity with Lawrence. But the Bills’ immense talent should ultimately rise to the top, even if it takes a while to show itself.’

‘”I’ve done it for less,” Allen joked, “but I think my standards are a little higher now. It’s gotta be a Super Bowl appearance and a Super Bowl win. I think as long as we get to the parade, maybe (I’ll do it) off the top rope of whatever bus I’m on … (Bills fans), they’re crazy. I love ’em. Bills Mafia, man, they are the hands-down best.”‘

‘”It’s good for me to get back to where I wanted to be, and it’s not on there,” Beasley said in a report by Syracuse.com. “The real world is out here and not there. Most people say things on there that you don’t want to hear. … I feel like I did the right thing and I’m going to stay off it.”‘

‘Rested up, Buffalo should have no problem moving the ball here. And that’s really all they need to secure a sweep of Miami while distancing themselves from the Patriots (3-4) in the division. Maybe, just maybe, the Dolphins will keep it close for a bit if they get creative with Waddle, Myles Gaskin and Mike Gesicki, playing keep-away. And you can bet Tua will be motivated to show out with the Watson rumors ongoing. But this one screams Bills victory.’

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‘Allen toured the 10th-floor wing, which also honors the 27,000 fans who donated to the Patricia Allen Fund with a playroom called the Bills Fans Fun Zone, on Tuesday.’

‘Knox suffered the injury prior to throwing a two-point conversion to Allen with 31 seconds remaining in the third quarter, giving the Bills a seven-point lead at the time. Allen, seemingly knowing something wasn’t quite right with his tight end, reportedly attempted to call the play off but went through with it after Knox insisted.’

‘Knox suffered the injury prior to throwing a two-point conversion to Allen with 31 seconds remaining in the third quarter, giving the Bills a seven-point lead at the time. Allen, seemingly knowing something wasn’t quite right with his tight end, reportedly attempted to call the play off but went through with it after Knox insisted.’

‘Derrick Henry once again had himself a monster evening, rushing 20 times for 143 yards and three touchdowns, including the game-winner late in the fourth quarter. The Titans were helped by several big plays, as well as several miscues by the Bills — with a holding penalty on a potential game-winning kick return taking a score off the board.’