‘Key matchup(s): Panthers RBs Rico Dowdle and Chuba Hubbard vs. Bills front seven. If the Panthers are going to have a chance against the Bills, they’ll need to control the time of possession and keep Josh Allen off the field. That means effectively running the football — something they have done extremely well of late. The Panthers have run for 580 yards over the past three games. They will again employ a two-back approach against the Bills. Last week Dowdle gained 79 yards rushing on 17 carries, while Hubbard had 14 carries for 31 yards. The vulnerable Bills defense comes into the game ranked 31st against the run, allowing 156.3 yards per game on the ground.’