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X’s and O’s: How 49ers’ run scheme will make Bills’ D react on the fly

‘Just like the Rams, the 49ers try to confuse the defense with misdirection. However, the run scheme of 49ers head coach Kyle Shanahan is more varied and complex than that of the Rams, because the 49ers use a lot of 21 personnel (fullback) and 12 personnel (two tight ends). The Rams used almost all 11 personnel (three wideouts) vs. the Bills.’

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